The Framingham Heart Study (FHS) began in 1949 with the goal of defining the
epidemiology of hypertensive or arteriosclerotic heart disease in the population of …

Cardiovascular diseases pose a huge threat to global human health and are also a major
obstacle to drug development and disease treatment. Drug-induced cardiotoxicity remains …

Background The diagnosis and prognosis of cardiovascular disorders are greatly aided by
cardiovascular biomarkers. The uses of troponin and B-type natriuretic peptide in situations …

Research background and Objectives: Age is an independent risk factor for cardiovascular
disease (CVD), but CVD risk factors are preventable, and lack of awareness of its risk factors …

Abstract Cytochrome P450 2J2 (CYP2J2) enzyme is widely expressed in aortic endothelial
cells and cardiac myocytes and affects cardiac function, but the underlying mechanism is still …

background This study investigated the relationship between combat-related traumatic injury
(CRTI) and its severity and predicted cardiovascular disease (CVD) risk. Material and …

Hypercholesterolemia plays a pivotal role in the development and progression of
cardiovascular diseases, and its prevention seems to be a crucial healthcare strategy to …

Background Previous work indicates that polygenic risk scores (PRS) for bipolar disorder
(BD) are elevated in adults and youth with BD, but whether BD-PRS can inform person-level …

Background Bipolar disorder (BD) conveys the highest risk of suicide of all mental disorders.
We sought to externally validate a risk calculator (RC) of suicide attempts developed in …

Metabolic syndrome (MS), a complex pathology with features like abnormal body fat
distribution, insulin resistance, and dyslipidaemia, contributes to higher cardiovascular (CV) …