The airway smooth muscle (ASM) cell plays a central role in the pathogenesis of asthma and
constitutes an important target for treatment. These cells control muscle tone and thus …

Chronic airflow limitation is the common denominator of patients with chronic obstructive
pulmonary disease (COPD). However, it is not possible to predict morbidity and mortality of …

For over 150 years, bronchoscopy, especially flexible bronchoscopy, has been a mainstay
for airway inspection, the diagnosis of airway lesions, therapeutic aspiration of airway …

Asthma affects over 300 million people worldwide and its prevalence is increasing. COPD is
the third leading cause of death globally. Asthma and COPD are complex inflammatory …

Background Bronchial thermoplasty regulates structural abnormalities involved in airway
narrowing in asthma. In the present study we aimed to investigate the effect of bronchial …

Increased airway smooth muscle mass, a feature of airway remodeling in asthma, is the
strongest predictor of airflow limitation and contributes to asthma-associated morbidity and …

The airway smooth muscle (ASM) surrounding the airways is dysfunctional in both asthma
and chronic obstructive pulmonary disease (COPD), exhibiting; increased contraction …

Rationale Bronchial thermoplasty is a mechanical therapeutic intervention that has been
advocated as an effective treatment option for severe asthma. The mechanism is promoted …

Background Increased airway smooth muscle mass is a key pathology in asthma. Bronchial
thermoplasty is a treatment for severe asthma based on selective heating of the airways that …

Purpose Bronchial thermoplasty is approved in many countries worldwide as a non-
pharmacological treatment for severe asthma. This review summarizes recent publications …