COVID-19 vaccine update: vaccine effectiveness, SARS-CoV-2 variants, boosters, adverse effects, and immune correlates of protection

WY Chi, YD Li, HC Huang, TEH Chan, SY Chow… - Journal of biomedical …, 2022 - Springer
Abstract Coronavirus Disease 2019 (COVID-19) has been the most severe public health
challenge in this century. Two years after its emergence, the rapid development and …

[HTML][HTML] SARS-CoV-2 reinfections: Overview of efficacy and duration of natural and hybrid immunity

S Pilz, V Theiler-Schwetz, C Trummer, R Krause… - Environmental …, 2022 - Elsevier
Seroprevalence surveys suggest that more than a third and possibly more than half of the
global population has been infected with SARS-CoV-2 by early 2022. As large numbers of …

Efficacy and safety of the RBD-dimer–based COVID-19 vaccine ZF2001 in adults

L Dai, L Gao, L Tao, SR Hadinegoro… - New England journal …, 2022 - Mass Medical Soc
Background The ZF2001 vaccine, which contains a dimeric form of the receptor-binding
domain of severe acute respiratory syndrome coronavirus 2 and aluminum hydroxide as an …

[HTML][HTML] Emerging variants of SARS-CoV-2 and novel therapeutics against coronavirus (COVID-19)

A Aleem, AS Ab, AK Slenker - 2021 - europepmc.org
Objectives: Describe the clinical manifestations, including extrapulmonary manifestations of
COVID-19. Outline the latest treatments available in the management of COVID-19 …

[HTML][HTML] Humoral and cellular immune memory to four COVID-19 vaccines

Z Zhang, J Mateus, CH Coelho, JM Dan… - Cell, 2022 - cell.com
Multiple COVID-19 vaccines, representing diverse vaccine platforms, successfully protect
against symptomatic COVID-19 cases and deaths. Head-to-head comparisons of T cell, B …

Efficacy of SARS-CoV-2 vaccines and the dose–response relationship with three major antibodies: a systematic review and meta-analysis of randomised controlled …

ZR Yang, YW Jiang, FX Li, D Liu, TF Lin… - The Lancet …, 2023 - thelancet.com
Background The efficacy of SARS-CoV-2 vaccines in preventing severe COVID-19 illness
and death is uncertain due to the rarity of data in individual trials. How well the antibody …

Effectiveness of COVID-19 vaccines against SARS-CoV-2 variants of concern: a systematic review and meta-analysis

B Zeng, L Gao, Q Zhou, K Yu, F Sun - BMC medicine, 2022 - Springer
Background It was urgent and necessary to synthesize the evidence for vaccine
effectiveness (VE) against SARS-CoV-2 variants of concern (VOC). We conducted a …

[HTML][HTML] Features, evaluation, and treatment of coronavirus (COVID-19)

M Cascella - 2020 - ncbi.nlm.nih.gov
Objectives: Screen individuals based on exposure and symptom criteria to identify potential
COVID-19 cases. Identify the clinical features and radiological findings expected in patients …

Effectiveness of heterologous and homologous covid-19 vaccine regimens: living systematic review with network meta-analysis

WY Au, PPH Cheung - Bmj, 2022 - bmj.com
Objective To evaluate the effectiveness of heterologous and homologous covid-19 vaccine
regimens with and without boosting in preventing covid-19 related infection, hospital …

[HTML][HTML] Antibodies from primary humoral responses modulate the recruitment of naive B cells during secondary responses

JMJ Tas, JH Koo, YC Lin, Z Xie, JM Steichen… - Immunity, 2022 - cell.com
Vaccines generate high-affinity antibodies by recruiting antigen-specific B cells to germinal
centers (GCs), but the mechanisms governing the recruitment to GCs on secondary …