Integrating dynamic reconfigurable DNA crosslinking units, smart DNA hydrogels have
demonstrated sol–gel transition, shape memory, self-healing, sensing, cargo encapsulation …

Recent advances in the understanding of the molecular mechanism of mRNA 3′ end
processing have uncovered a previously unanticipated integrated network of transcriptional …

Reactive oxygen species are required for cell proliferation but can also induce apoptosis. In
proliferating cells this paradox is solved by the activation of protein kinase B (PKB; also …

Pre-mRNA 3′ end formation is an essential step in eukaryotic gene expression. Over half of
human genes produce alternatively polyadenylated mRNAs, suggesting that regulated …

Messenger RNA regulation is a critical mode of controlling gene expression. Regulation of
mRNA stability and translation is linked to controls of poly (A) tail length,. Poly (A) …

Poly (A) tail elongation after export of an messenger RNA (mRNA) to the cytoplasm is called
cytoplasmic polyadenylation. It was first discovered in oocytes and embryos, where it has …

The 3′‐ends of almost all eukaryotic mRNAs are formed in a two‐step process, an
endonucleolytic cleavage followed by polyadenylation (the addition of a poly‐adenosine or …

Translation initiation is regulated in response to nutrient availability and mitogenic
stimulation and is coupled with cell cycle progression and cell growth. Several alterations in …

At least half of all human pre-mRNAs are subject to alternative 3′ processing that may
modulate both the coding capacity of the message and the array of post-transcriptional …

RNA-specific nucleotidyl transferases (rNTrs) are a diverse family of template-independent
polymerases that add ribonucleotides to the 3′-ends of RNA molecules. All rNTrs share a …