[HTML][HTML] Red blood cell storage lesion: causes and potential clinical consequences

T Yoshida, M Prudent, A D'Alessandro - Blood Transfusion, 2019 - ncbi.nlm.nih.gov
Red blood cells (RBCs) are a specialised organ that enabled the evolution of multicellular
organisms by supplying a sufficient quantity of oxygen to cells that cannot obtain oxygen …

[HTML][HTML] Red blood cell storage time and transfusion: current practice, concerns and future perspectives

M García-Roa, M del Carmen Vicente-Ayuso… - Blood …, 2017 - ncbi.nlm.nih.gov
Red blood cells (RBCs) units are the most requested transfusion product worldwide.
Indications for transfusion include symptomatic anaemia, acute sickle cell crisis, and acute …

The effect of deformability on the microscale flow behavior of red blood cell suspensions

A Passos, JM Sherwood, E Kaliviotis, R Agrawal… - Physics of …, 2019 - pubs.aip.org
Red blood cell (RBC) deformability is important for tissue perfusion and a key determinant of
blood rheology. Diseases such as diabetes, sickle cell anemia, and malaria, as well as …

Atomic force microscopy and high-resolution spectrophotometry for study of anoxemia and normoxemia in model experiment in vitro

E Kozlova, E Sherstyukova, V Sergunova… - International Journal of …, 2023 - mdpi.com
The oxygen content in the blood may decrease under the influence of various
physicochemical factors and different diseases. The state of hypoxemia is especially …

[HTML][HTML] Hypoxically stored RBC resuscitation in a rat model of traumatic brain injury and severe hemorrhagic shock

CR Muller, V Courelli, K Govender, L Omert, T Yoshida… - Life Sciences, 2024 - Elsevier
This study aims to investigate the effects of hypoxically stored Red Blood Cells (RBCs) in a
rat model of traumatic brain injury followed by severe hemorrhagic shock (HS) and …

Advances in mechanical biomarkers

M Eroles, F Rico - Journal of Molecular Recognition, 2023 - Wiley Online Library
Mechanical biomarkers distinguish health conditions through quantitative mechanical
measurements. The emergence and establishment of nanotechnology in the last decades …

Deep ensemble learning enables highly accurate classification of stored red blood cell morphology

AH Routt, N Yang, NZ Piety, M Lu, SS Shevkoplyas - Scientific Reports, 2023 - nature.com
Abstract Changes in red blood cell (RBC) morphology distribution have emerged as a
quantitative biomarker for the degradation of RBC functional properties during hypothermic …

Oxidative stress and antioxidant defenses during blood processing and storage of erythrocyte concentrates

M Bardyn, JD Tissot, M Prudent - Transfusion Clinique et Biologique, 2018 - Elsevier
Oxidative lesions start accumulating in cells when the oxidant attacks overwhelm the
antioxidant defenses. This review will briefly describe red blood cell storage lesions with …

Intermittent scavenging of storage lesion from stored red blood cells by electrospun nanofibrous sheets enhances their quality and shelf-life

S Pandey, M Mahato, P Srinath, U Bhutani… - Nature …, 2022 - nature.com
Transfusion of healthy red blood cells (RBCs) is a lifesaving process. However, upon storing
RBCs, a wide range of damage-associate molecular patterns (DAMPs), such as cell-free …

Microfluidic capillary networks are more sensitive than ektacytometry to the decline of red blood cell deformability induced by storage

NZ Piety, J Stutz, N Yilmaz, H Xia, T Yoshida… - Scientific Reports, 2021 - nature.com
Ektacytometry has been the primary method for evaluating deformability of red blood cells
(RBCs) in both research and clinical settings. This study was designed to test the hypothesis …