[HTML][HTML] Gene regulatory networks and transcriptional mechanisms that control myogenesis
M Buckingham, PWJ Rigby - Developmental cell, 2014 - cell.com
We discuss the upstream regulators of myogenesis that lead to the activation of myogenic
determination genes and subsequent differentiation, focusing on the mouse model. Key …
determination genes and subsequent differentiation, focusing on the mouse model. Key …
Regulation of muscle stem cell functions: a focus on the p38 MAPK signaling pathway
J Segalés, E Perdiguero… - Frontiers in cell and …, 2016 - frontiersin.org
Formation of skeletal muscle fibers (myogenesis) during development and after tissue injury
in the adult constitutes an excellent paradigm to investigate the mechanisms whereby …
in the adult constitutes an excellent paradigm to investigate the mechanisms whereby …
UTX mutations in human cancer
L Wang, A Shilatifard - Cancer cell, 2019 - cell.com
Ubiquitously transcribed tetratricopeptide repeat on chromosome X (UTX, encoded by
KDM6A) is a histone demethylase that targets di-and tri-methylated histone H3 lysine 27 …
KDM6A) is a histone demethylase that targets di-and tri-methylated histone H3 lysine 27 …
Histone demethylases in chromatin biology and beyond
E Dimitrova, AH Turberfield, RJ Klose - EMBO reports, 2015 - embopress.org
Histone methylation plays fundamental roles in regulating chromatin‐based processes. With
the discovery of histone demethylases over a decade ago, it is now clear that histone …
the discovery of histone demethylases over a decade ago, it is now clear that histone …
Chemotherapy-induced S100A10 recruits KDM6A to facilitate OCT4-mediated breast cancer stemness
Breast cancer stem cells (BCSCs) play a critical role in cancer recurrence and metastasis.
Chemotherapy induces BCSC specification through increased expression of pluripotency …
Chemotherapy induces BCSC specification through increased expression of pluripotency …
Molecular and cellular regulation of skeletal myogenesis
G Comai, S Tajbakhsh - Current topics in developmental biology, 2014 - Elsevier
Since the seminal discovery of the cell-fate regulator Myod, studies in skeletal myogenesis
have inspired the search for cell-fate regulators of similar potential in other tissues and …
have inspired the search for cell-fate regulators of similar potential in other tissues and …
[HTML][HTML] Identification of gene positioning factors using high-throughput imaging mapping
Genomes are arranged non-randomly in the 3D space of the cell nucleus. Here, we have
developed HIPMap, a high-precision, high-throughput, automated fluorescent in situ …
developed HIPMap, a high-precision, high-throughput, automated fluorescent in situ …
The H3K27me3 demethylase UTX in normal development and disease
J Van der Meulen, F Speleman, P Van Vlierberghe - Epigenetics, 2014 - Taylor & Francis
In 2007, the Ubiquitously Transcribed Tetratricopeptide Repeat on chromosome X (UTX)
was identified as a histone demethylase that specifically targets di-and tri-methyl groups on …
was identified as a histone demethylase that specifically targets di-and tri-methyl groups on …
KDM6 demethylase independent loss of histone H3 lysine 27 trimethylation during early embryonic development
KB Shpargel, J Starmer, D Yee, M Pohlers… - PLoS …, 2014 - journals.plos.org
The early mammalian embryo utilizes histone H3 lysine 27 trimethylation (H3K27me3) to
maintain essential developmental genes in a repressive chromatin state. As differentiation …
maintain essential developmental genes in a repressive chromatin state. As differentiation …
Time-resolved global and chromatin proteomics during herpes simplex virus type 1 (HSV-1) infection
Herpes simplex virus (HSV-1) lytic infection results in global changes to the host cell
proteome and the proteins associated with host chromatin. We present a system level …
proteome and the proteins associated with host chromatin. We present a system level …