Plant viral diseases are the foremost threat to sustainable agriculture, leading to several
billion dollars in losses every year. Many viruses infecting several crops have been …

Viruses are ubiquitous in the environment. While many impart no deleterious effects on their
hosts, several are major pathogens. This risk of pathogenicity, alongside the fact that many …

The survival rate following lung transplantation is among the lowest of all solid-organ
transplants, and current diagnostic tests often fail to distinguish between infection and …

Next-generation sequencing (NGS) technology has shown promise for the detection of
human pathogens from clinical samples. However, one of the major obstacles to the use of …

Motivation High-throughput sequencing technologies are used increasingly not only in viral
genomics research but also in clinical surveillance and diagnostics. These technologies …

Population (Sanger) sequencing has been the standard method in basic and clinical DNA
sequencing for almost 40 years; however, next-generation (deep) sequencing …

Influenza epidemics and pandemics have significant impacts on economies, morbidity and
mortality worldwide. The ability to rapidly and accurately sequence influenza viruses is …

Viral infections are responsible for the deaths of millions of people throughout the world.
Since outbreak of highly contagious and mutant viruses such as contemporary sars-cov-2 …

As in other medical fields, the availability of next generation sequencing (NGS) techniques is
about to revolutionize diagnostics of infectious diseases. The demonstration of the microbial …

The majority of new and existing cases of HCV infection in high-income countries occur
among people who inject drugs (PWID). Ongoing high-risk behaviours can lead to HCV re …