The molecular biology in wound healing & non-healing wound

C Qing - Chinese Journal of Traumatology, 2017 - mednexus.org
The development of molecular biology and other new biotechnologies helps us to recognize
the wound healing and non-healing wound of skin in the past 30 years. This review mainly …

Endothelial dysfunction and diabetes: effects on angiogenesis, vascular remodeling, and wound healing

GK Kolluru, SC Bir, CG Kevil - International journal of vascular …, 2012 - Wiley Online Library
Diabetes mellitus (DM) is a chronic metabolic disorder characterized by inappropriate
hyperglycemia due to lack of or resistance to insulin. Patients with DM are frequently afflicted …

New insight into dyslipidemia‐induced cellular senescence in atherosclerosis

Q Xiang, F Tian, J Xu, X Du, S Zhang… - Biological Reviews, 2022 - Wiley Online Library
Atherosclerosis, characterized by lipid‐rich plaques in the arterial wall, is an age‐related
disorder and a leading cause of mortality worldwide. However, the specific mechanisms …

Critical reevaluation of endothelial progenitor cell phenotypes for therapeutic and diagnostic use

GP Fadini, D Losordo, S Dimmeler - Circulation research, 2012 - Am Heart Assoc
Diverse subsets of endothelial progenitor cells (EPCs) are used for the treatment of ischemic
diseases in clinical trials, and circulating EPCs levels are considered as biomarkers for …

Molecular analysis of endothelial progenitor cell (EPC) subtypes reveals two distinct cell populations with different identities

RJ Medina, CL O'Neill, M Sweeney… - BMC medical …, 2010 - Springer
Background The term endothelial progenitor cells (EPCs) is currently used to refer to cell
populations which are quite dissimilar in terms of biological properties. This study provides a …

MiR-146a as marker of senescence-associated pro-inflammatory status in cells involved in vascular remodelling

F Olivieri, R Lazzarini, R Recchioni, F Marcheselli… - Age, 2013 - Springer
In order to identify new markers of vascular cell senescence with potential in vivo
implications, primary cultured endothelial cells, including human umbilical vein endothelial …

Circulating endothelial cells, microparticles and progenitors: key players towards the definition of vascular competence

F Sabatier, L Camoin‐Jau, F Anfosso… - Journal of cellular …, 2009 - Wiley Online Library
• Introduction• Dynamics between endothelial injury and repair: the response to injury theory
'revisited'• Emerging biomarkers reflecting the dynamics between endothelial injury and …

Induction of EPC homing on biofunctionalized vascular grafts for rapid in vivo self-endothelialization—a review of current strategies

M Avci-Adali, G Ziemer, HP Wendel - Biotechnology advances, 2010 - Elsevier
For years intensive research has been done to improve the hemocompatibility of blood
contacting vascular devices. Despite the enormous progress in physicochemical surface …

Circulating stem cells and cardiovascular outcomes: from basic science to the clinic

GP Fadini, A Mehta, DS Dhindsa… - European heart …, 2020 - academic.oup.com
The cardiovascular and haematopoietic systems have fundamental inter-relationships
during development, as well as in health and disease of the adult organism. Although …

Time course and mechanisms of circulating progenitor cell reduction in the natural history of type 2 diabetes

GP Fadini, E Boscaro, S De Kreutzenberg… - Diabetes …, 2010 - Am Diabetes Assoc
OBJECTIVE Reduction of bone marrow–derived circulating progenitor cells has been
proposed as a novel mechanism of cardiovascular disease in type 2 diabetes. The present …