Advances in preclinical research models of radiation-induced cardiac toxicity
RA Schlaak, G SenthilKumar, M Boerma, C Bergom - Cancers, 2020 - mdpi.com
Radiation therapy (RT) is an important component of cancer therapy, with> 50% of cancer
patients receiving RT. As the number of cancer survivors increases, the short-and long-term …
patients receiving RT. As the number of cancer survivors increases, the short-and long-term …
Rapid recruitment and IFN-I–mediated activation of monocytes dictate focal radiotherapy efficacy
The recruitment of monocytes and their differentiation into immunosuppressive cells is
associated with the low efficacy of preclinical nonconformal radiotherapy (RT) for tumors …
associated with the low efficacy of preclinical nonconformal radiotherapy (RT) for tumors …
Design optimization of an electron-to-photon conversion target for ultra-high dose rate x-ray (FLASH) experiments at TRIUMF
N Esplen, L Egoriti, B Paley, T Planche… - Physics in Medicine …, 2022 - iopscience.iop.org
Objective. To develop a bremsstrahlung target and megavoltage (MV) x-ray irradiation
platform for ultrahigh dose-rate (UHDR) irradiation of small-animals on the Advanced Rare …
platform for ultrahigh dose-rate (UHDR) irradiation of small-animals on the Advanced Rare …
Monte Carlo simulations of EBT3 film dose deposition for percentage depth dose (PDD) curve evaluation
SM Robinson, N Esplen, D Wells… - Journal of Applied …, 2020 - Wiley Online Library
Abstract Purpose To use Monte Carlo (MC) calculations to evaluate the effects of Gafchromic
EBT3 film orientation on percentage depth dose (PDD) curves. Methods Dose deposition in …
EBT3 film orientation on percentage depth dose (PDD) curves. Methods Dose deposition in …
Current instrumentation and technologies in modern radiobiology research—opportunities and challenges
E Ford, J Deye - Seminars in radiation oncology, 2016 - Elsevier
There is a growing awareness of the gaps in the technical methods employed in radiation
biology experiments. These quality gaps can have a substantial effect on the reliability and …
biology experiments. These quality gaps can have a substantial effect on the reliability and …
Impact of backscatter material thickness on the depth dose of orthovoltage irradiators for radiobiology research
Q Chen, J Molloy, T Izumi… - Physics in Medicine & …, 2019 - iopscience.iop.org
The orthovoltage x-ray energy frequently used in radiation research is prone to dosimetry
errors due to insufficient backscatter conditions. In many radiobiology studies, especially for …
errors due to insufficient backscatter conditions. In many radiobiology studies, especially for …
A framework for inverse planning of beam-on times for 3D small animal radiotherapy using interactive multi-objective optimisation
M Balvert, SJ van Hoof, PV Granton… - Physics in Medicine …, 2015 - iopscience.iop.org
Advances in precision small animal radiotherapy hardware enable the delivery of
increasingly complicated dose distributions on the millimeter scale. Manual creation and …
increasingly complicated dose distributions on the millimeter scale. Manual creation and …
A kernel-based dose calculation algorithm for kV photon beams with explicit handling of energy and material dependencies
Objective: Mimicking state-of-the-art patient radiotherapy with high-precision irradiators for
small animals is expected to advance the understanding of dose–effect relationships and …
small animals is expected to advance the understanding of dose–effect relationships and …
Scattered dose calculations and measurements in a life-like mouse phantom
D Welch, L Turner, M Speiser… - Radiation …, 2017 - meridian.allenpress.com
Anatomically accurate phantoms are useful tools for radiation dosimetry studies. In this work,
we demonstrate the construction of a new generation of life-like mouse phantoms in which …
we demonstrate the construction of a new generation of life-like mouse phantoms in which …
18F-EF5 PET Is Predictive of Response to Fractionated Radiotherapy in Preclinical Tumor Models
We evaluated the relationship between pre-treatment positron emission tomography (PET)
using the hypoxic tracer 18F-[2-(2-nitro-1-H-imidazol-1-yl)-N-(2, 2, 3, 3, 3-pentafluoropropyl) …
using the hypoxic tracer 18F-[2-(2-nitro-1-H-imidazol-1-yl)-N-(2, 2, 3, 3, 3-pentafluoropropyl) …