A highly conserved but convoluted network of neurons and glial cells, the enteric nervous
system (ENS), is positioned along the wall of the gut to coordinate digestive processes and …

Autism spectrum disorders (ASDs) are recognized as central neurodevelopmental disorders
diagnosed by impairments in social interactions, communication and repetitive behaviours …

In the United States, gastrointestinal disorders account for in excess of $130 billion in
healthcare expenditures and 22 million hospitalizations annually. Many of these disorders …

Emerging evidence have shown the importance of gut microbiota in regulating brain
functions. The diverse molecular mechanisms involved in cross-talk between gut and brain …

Selenium (Se) is an essential trace element in the body. It is mainly used in the body in the
form of selenoproteins and has a variety of biological functions. Intestinal diseases caused …

Infants and young children receive the highest exposures to antibiotics globally. Although
there is building evidence that early life exposure to antibiotics increases susceptibility to …

Second only to early life, adolescence is a period of dramatic change and growth. For the
developing young adult, this occurs against a backdrop of distinct environmental challenges …

Modern research on gastrointestinal behavior has revealed it to be a highly complex
bidirectional process in which the gut sends signals to the brain, via spinal and vagal …

Interactions between the enteric nervous system (ENS), immune system, and gut microbiota
regulate intestinal homeostasis in adults, but their development and role (s) in early life are …

Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder that is more common
in females. Despite its high global incidence, the disease mechanism is still unclear and …