Sixteen years ago, the Nomenclature Committee of the International Union of Pharmacology
approved a system for naming human seven-transmembrane (7TM) G protein-coupled …

▪ Abstract In addition to CD4, the human immunodeficiency virus (HIV) requires a coreceptor
for entry into target cells. The chemokine receptors CXCR4 and CCR5, members of the G …

Summary The World Health Organization has declared SARS-CoV-2 virus outbreak a
worldwide pandemic. However, there is very limited understanding on the immune …

Macrophages have long been considered to contribute to HIV infection of the CNS; however,
a recent study has contradicted this early work and suggests that myeloid cells are not an in …

Given its population of CCR5-expressing, immunologically activated CD4+ T cells, the
gastrointestinal (GI) mucosa is uniquely susceptible to human immunodeficiency virus (HIV) …

CXCL16 is a chemotactic cytokine belonging to the α-chemokine subfamily. It plays a
significant role in the progression of cancer, as well as the course of atherosclerosis, renal …

Most of the human genome has now been sequenced and about 30,000 potential open
reading frames have been identified, indicating that we use these 30,000 genes to …

We describe a protein with the hallmarks of a chemokine, designated CXCL16, that is made
by dendritic cells (DCs) in lymphoid organ T cell zones and by cells in the splenic red pulp …

ABSTRACT T-20 is a synthetic peptide that potently inhibits replication of human
immunodeficiency virus type 1 by interfering with the transition of the transmembrane …

We examined the in vivo behavior of liver natural killer T cells (NKT cells) by intravital
fluorescence microscopic imaging of mice in which a green fluorescent protein cDNA was …