Biomarker development for axial spondyloarthritis
The term axial spondyloarthritis (axSpA) encompasses a heterogeneous group of diseases
that have variable presentations, extra-articular manifestations and clinical outcomes, and …
that have variable presentations, extra-articular manifestations and clinical outcomes, and …
Peripheral blood RNA biomarkers for cardiovascular disease from bench to bedside: a position paper from the EU-CardioRNA COST action CA17129
M Vanhaverbeke, R Attard, M Bartekova… - Cardiovascular …, 2022 - academic.oup.com
Despite significant advances in the diagnosis and treatment of cardiovascular diseases,
recent calls have emphasized the unmet need to improve precision-based approaches in …
recent calls have emphasized the unmet need to improve precision-based approaches in …
Sexual dimorphism in the Th17 signature of ankylosing spondylitis
E Gracey, YC Yao, B Green, Z Qaiyum… - Arthritis & …, 2016 - Wiley Online Library
Objective To identify an immunologic basis for the male sex bias in ankylosing spondylitis
(AS). Methods Cohorts of male and female patients with AS and age‐and sex‐matched …
(AS). Methods Cohorts of male and female patients with AS and age‐and sex‐matched …
Upregulated of ANXA3, SORL1, and neutrophils may be key factors in the progressionof ankylosing spondylitis
J Jiang, X Zhan, H Qu, T Liang, H Li, L Chen… - Frontiers in …, 2022 - frontiersin.org
Introduction The specific pathogenesis of ankylosing spondylitis (AS) remains unclear, and
our study aimed to investigate the possible pathogenesis of AS. Materials and Methods Two …
our study aimed to investigate the possible pathogenesis of AS. Materials and Methods Two …
Genetics and functional genomics of spondyloarthritis
Spondyloarthritis (SpA) is a chronic inflammatory disorder with high heritability but with
complex genetics. It encompasses several entities that share common clinical features. Most …
complex genetics. It encompasses several entities that share common clinical features. Most …
[HTML][HTML] Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis
AC Brown, CJ Cohen, O Mielczarek, G Migliorini… - Cell Genomics, 2023 - cell.com
Ankylosing spondylitis (AS) is a common, highly heritable inflammatory arthritis
characterized by enthesitis of the spine and sacroiliac joints. Genome-wide association …
characterized by enthesitis of the spine and sacroiliac joints. Genome-wide association …
Excessive bone formation in a mouse model of ankylosing spondylitis is associated with decreases in Wnt pathway inhibitors
KR Haynes, AR Pettit, R Duan, HW Tseng… - Arthritis research & …, 2012 - Springer
Introduction Ankylosing spondylitis (AS) is unique in its pathology where inflammation
commences at the entheses before progressing to an osteoproliferative phenotype …
commences at the entheses before progressing to an osteoproliferative phenotype …
Evaluation of DNMT1 gene expression profile and methylation of its promoter region in patients with ankylosing spondylitis
Ankylosing spondylitis (AS) is an autoimmune disease with a chronic inflammatory arthritis.
The critical role of methylation in the biology of immunocytes has increasingly been …
The critical role of methylation in the biology of immunocytes has increasingly been …
Identification of breast cancer mechanism based on weighted gene coexpression network analysis
X Guo, H Xiao, S Guo, L Dong, J Chen - Cancer gene therapy, 2017 - nature.com
Our gene expression-profiling analysis aimed to explain the mechanism of breast cancer
development by identifying key pathways and constructing networks of related transcription …
development by identifying key pathways and constructing networks of related transcription …
Single‐cell RNA‐seq reveals altered NK cell subsets and reduced levels of cytotoxic molecules in patients with ankylosing spondylitis
C Ren, M Li, Y Zheng, B Cai, W Du… - Journal of Cellular …, 2022 - Wiley Online Library
Ankylosing spondylitis (AS) is an autoimmune disease with unknown aetiology. To unravel
the mechanisms mediating AS pathogenesis, we profiled peripheral blood mononuclear …
the mechanisms mediating AS pathogenesis, we profiled peripheral blood mononuclear …