The glutathione (GSH) system is considered to be one of the most powerful endogenous
antioxidant systems in the cardiovascular system due to its key contribution to detoxifying …

Left ventricular ejection fraction (LVEF) has been the central parameter used for diagnosis
and management in patients with heart failure. A good predictor of adverse outcomes in …

Background: The morbidity and mortality of patients with functional mitral regurgitation (MR)
remain high, but no pharmacological therapy has been proven effective. The hypothesis of …

Background Ischemic mitral regurgitation is associated with a substantial risk of death.
Practice guidelines recommend surgery for patients with a severe form of this condition but …

Secondary (or functional) mitral regurgitation (SMR) occurs frequently in chronic heart failure
(HF) with reduced left ventricular (LV) ejection fraction, resulting from LV remodelling that …

In response to injury, hemodynamic changes, or neurohormonal activation, the heart
undergoes a series of structural and functional changes that have been termed cardiac …

Ventricular remodeling, first described in animal models of left ventricular (LV) stress and
injury, occurs progressively in untreated patients after large myocardial infarction and in …

Abstract Purpose of Review The purpose of this review it to summarize the current literature
on remodeling after myocardial infarction, inclusive of pathophysiological considerations …

Background—Phase I clinical studies have demonstrated the feasibility of implanting
autologous skeletal myoblasts in postinfarction scars. However, they have failed to …

Objectives: This study sought to evaluate the incidence, the predictors, and the associations
with outcomes of changes in ejection fraction (EF) in heart failure (HF) patients. Background …