Despite enormous progress in understanding the fundamentals of bacterial gene regulation,
our knowledge remains limited when compared with the number of bacterial genomes and …

When investigating Mendelian disease using exome or genome sequencing, distinguishing
disease-causing genetic variants from the multitude of candidate variants is a complex …

FlyBase provides a centralized resource for the genetic and genomic data of Drosophila
melanogaster. As FlyBase enters our fourth decade of service to the research community …

Abstract The Catalogue Of Somatic Mutations In Cancer (COSMIC), https://cancer. sanger.
ac. uk/cosmic, is an expert-curated knowledgebase providing data on somatic variants in …

Summary The American College of Medical Genetics and Genomics (ACMG)/Association for
Molecular Pathology (AMP) framework for classifying variants uses six evidence categories …

Public databases contain a planetary collection of nucleic acid sequences, but their
systematic exploration has been inhibited by a lack of efficient methods for searching this …

RNAcentral is a comprehensive database of non-coding RNA (ncRNA) sequences that
provides a single access point to 44 RNA resources and> 18 million ncRNA sequences from …

The Rfam database is a collection of RNA families in which each family is represented by a
multiple sequence alignment, a consensus secondary structure, and a covariance model. In …

While long non-coding RNA (lncRNA) research in the past has primarily focused on the
discovery of novel genes, today it has shifted towards functional annotation of this large …

CIViC is an expert-crowdsourced knowledgebase for Clinical Interpretation of Variants in
Cancer describing the therapeutic, prognostic, diagnostic and predisposing relevance of …