Same species, different diseases: how and why typhoidal and non-typhoidal Salmonella enterica serovars differ

O Gal-Mor, EC Boyle, GA Grassl - Frontiers in microbiology, 2014 - frontiersin.org
Human infections by the bacterial pathogen Salmonella enterica represent major disease
burdens worldwide. This highly ubiquitous species consists of more than 2600 different …

Salmonella enterica Serovar Typhi and the Pathogenesis of Typhoid Fever

G Dougan, S Baker - Annual review of microbiology, 2014 - annualreviews.org
Salmonella enterica serovar Typhi, the cause of typhoid, is host restricted to humans. S.
Typhi has a monophyletic population structure, indicating that typhoid in humans is a …

Precision editing of the gut microbiota ameliorates colitis

W Zhu, MG Winter, MX Byndloss, L Spiga, BA Duerkop… - Nature, 2018 - nature.com
Inflammatory diseases of the gastrointestinal tract are frequently associated with
dysbiosis,,,,,,,, characterized by changes in gut microbial communities that include an …

Host–pathogen interaction in invasive salmonellosis

HK De Jong, CM Parry, T van der Poll, WJ Wiersinga - 2012 - journals.plos.org
Salmonella enterica infections result in diverse clinical manifestations. Typhoid fever,
caused by S. enterica serovar Typhi (S. Typhi) and S. Paratyphi A, is a bacteremic illness but …

Typhoidal Salmonella: Distinctive virulence factors and pathogenesis

R Johnson, E Mylona, G Frankel - Cellular microbiology, 2018 - Wiley Online Library
Although nontyphoidal Salmonella (NTS; including Salmonella Typhimurium) mainly cause
gastroenteritis, typhoidal serovars (Salmonella Typhi and Salmonella Paratyphi A) cause …

Salmonella Biofilm Formation, Chronic Infection, and Immunity Within the Intestine and Hepatobiliary Tract

JE Harrell, MM Hahn, SJ D'Souza… - Frontiers in cellular …, 2021 - frontiersin.org
Within the species of Salmonella enterica, there is significant diversity represented among
the numerous subspecies and serovars. Collectively, these account for microbes with …

Salmonella–Host Interactions – Modulation of the Host Innate Immune System

D Hurley, MP McCusker, S Fanning… - Frontiers in …, 2014 - frontiersin.org
Salmonella enterica (S. enterica) are Gram-negative bacteria that can invade a broad range
of hosts causing both acute and chronic infections. This phenotype is related to its ability to …

Iron acquisition by a commensal bacterium modifies host nutritional immunity during Salmonella infection

L Spiga, RT Fansler, YR Perera, NG Shealy… - Cell Host & Microbe, 2023 - cell.com
During intestinal inflammation, host nutritional immunity starves microbes of essential
micronutrients, such as iron. Pathogens scavenge iron using siderophores, including …

Salmonella Virulence and Immune Escape

M Wang, IH Qazi, L Wang, G Zhou, H Han - Microorganisms, 2020 - mdpi.com
Salmonella genus represents the most common foodborne pathogens causing morbidity,
mortality, and burden of disease in all regions of the world. The introduction of antimicrobial …

Curli-containing enteric biofilms inside and out: matrix composition, immune recognition, and disease implications

SA Tursi, Ç Tükel - Microbiology and Molecular Biology Reviews, 2018 - Am Soc Microbiol
Biofilms of enteric bacteria are highly complex, with multiple components that interact to
fortify the biofilm matrix. Within biofilms of enteric bacteria such as Escherichia coli and …