Combatting the ever-increasing threat from invasive fungal pathogens faces numerous
fundamental challenges, including constant human exposure to large reservoirs of species …

Fungal insect pathogens have evolved diverse mechanisms to evade host immune
recognition and defense responses. However, identification of fungal factors involved in host …

In recent years, fungal vaccine research emanated significant findings in the field of
antifungal T-cell immunity. The generation of effector T cells is essential to combat many …

Candida albicans exists as a commensal of mucosal surfaces and the gastrointestinal tract
without causing pathology. However, this fungus is also a common cause of mucosal and …

The immunogenicity of Candida albicans cells is influenced by changes in the exposure of
microbe-associated molecular patterns (MAMPs) on the fungal cell surface. Previously, the …

The cell wall of human fungal pathogens plays critical roles as an architectural scaffold and
as a target and modulator of the host immune response. Although the cell wall of the …

Probiotics are defined as live organisms in the host that contribute to health benefits.
Lactobacillus gasseri LM1065, isolated from human breast milk, was investigated for its …

Microbial species capable of co-existing with healthy individuals, such as the commensal
fungus Candida albicans, exploit multifarious strategies to evade our immune defenses …

We are constantly exposed to the threat of fungal infection. The outcome—clearance,
commensalism or infection—depends largely on the ability of our innate immune defences …

Patients with decreased levels of CD18 (β2 integrins) suffer from life-threatening bacterial
and fungal infections. CD11b, the α subunit of integrin CR3 (CD11b/CD18, αMβ2), is …