'Magnesium'-the master cation-as a drug—possibilities and evidences

AA Mathew, R Panonnummal - Biometals, 2021 - Springer
Abstract Magnesium (Mg2+) is the 2nd most abundant intracellular cation, which participates
in various enzymatic reactions; there by regulating vital biological functions. Magnesium …

Nutrients to improve mitochondrial function to reduce brain energy deficit and oxidative stress in migraine

M Fila, C Chojnacki, J Chojnacki, J Blasiak - Nutrients, 2021 - mdpi.com
The mechanisms of migraine pathogenesis are not completely clear, but 31P-nuclear
magnetic resonance studies revealed brain energy deficit in migraineurs. As glycolysis is the …

Magnesium as an important factor in the pathogenesis and treatment of migraine—from theory to practice

I Domitrz, J Cegielska - Nutrients, 2022 - mdpi.com
So far, no coherent and convincing theory has been developed to fully explain the
pathogenesis of migraine, although many researchers and experts emphasize its …

Magnesium for pain treatment in 2021? State of the art

V Morel, ME Pickering, J Goubayon, M Djobo… - Nutrients, 2021 - mdpi.com
Background: Magnesium (Mg) is commonly used in clinical practice for acute and chronic
pain and has been reported to reduce pain intensity and analgesics consumption in a …

Testing the role of glutamate NMDA receptors in peripheral trigeminal nociception implicated in migraine pain

C Guerrero-Toro, K Koroleva, E Ermakova… - International Journal of …, 2022 - mdpi.com
The pro-nociceptive role of glutamate in the CNS in migraine pathophysiology is well
established. Glutamate, released from trigeminal afferents, activates second order …

Recent advancements in Mg-based micromotors for biomedical and environmental applications

Y Wang, B Qin, S Gao, X Wang, H Zhang… - Journal of Materials …, 2023 - pubs.rsc.org
Synthetic micro/nanomotors have attracted considerable attention due to their promising
potential in the field of biomedicine. Despite their great potential, major micromotors require …

Editorial of Special Issue “magnesium in human health and disease”

S Castiglioni - Nutrients, 2021 - mdpi.com
The fundamental role of magnesium in human health is extensively discussed in the review
by Fiorentini and colleagues [1]. Magnesium acts both as a signalling element and a …

A mini review on the various facets effecting brain delivery of magnesium and its role in neurological disorders

AA Mathew, R Panonnummal - Biological Trace Element Research, 2023 - Springer
Magnesium is an essential cation present in the body that participates in the regulation of
various vital body functions. Maintaining normal level of magnesium is essential for proper …

Pediatric headache in primary care and emergency departments: consensus with RAND/UCLA method

G Prezioso, A Suppiej, V Alberghini, P Bergonzini… - Life, 2022 - mdpi.com
Headache is the most frequent neurological symptom in childhood and the main reason for
admission to pediatric emergency departments. The aim of this consensus document is to …

ATP line splitting in association with reduced intracellular magnesium and pH: a brain 31P MR spectroscopic imaging (MRSI) study of pediatric patients with myelin …

J Ren, F Yu, BM Greenberg - NMR in Biomedicine, 2023 - Wiley Online Library
Over the past four decades, ATP, the obligatory energy molecule for keeping all cells alive
and functioning, has been thought to contribute only one set of signals in brain 31P MR …