Recent advances in cyclization reactions of isatins or thioisatins via C–N or C–S bond cleavage
J Shen, L Zhang, X Meng - Organic Chemistry Frontiers, 2021 - pubs.rsc.org
The exploration of new reactivity modes and synthetic methods has always been an
attractive goal of organic and medicinal chemistry. As potential raw materials for the efficient …
attractive goal of organic and medicinal chemistry. As potential raw materials for the efficient …
Discovery of tryptanthrin and its derivatives and its activities against NSCLC in vitro via both apoptosis and autophagy pathways
Y Zou, G Zhang, C Li, H Long, D Chen, Z Li… - International Journal of …, 2023 - mdpi.com
In this study, a series of novel tryptanthrin derivatives were synthesized and their inhibitory
activities against selected human cancer cell lines, namely, lung (A549), chronic myeloid …
activities against selected human cancer cell lines, namely, lung (A549), chronic myeloid …
Green synthesis and antibacterial evaluation of spiro fused tryptanthrin-thiopyrano [2, 3-b] indole hybrids targeting drug-resistant S. aureus
Green and facile synthesis of 24 tryptanthrin-thiopyrano [2, 3-b] indole hybrid molecules is
described (i) by a thermal one-pot multi-component strategy,(ii) using ammonium acetate in …
described (i) by a thermal one-pot multi-component strategy,(ii) using ammonium acetate in …
Tryptanthrin and its derivatives in drug discovery: synthetic insights
Tryptanthrin is a golden-yellow, naturally occurring alkaloid that can be obtained from
multiple sources and through different synthetic methodologies. This tetracyclic compound …
multiple sources and through different synthetic methodologies. This tetracyclic compound …
Visible‐Light‐Induced Aerobic Intramolecular Cyclization of (2‐Aminophenyl)(1H‐indol‐1‐yl)methanones: Direct Access to Bioactive Tryptanthrin and its Derivatives
M Arockiaraj, G Singh, S Sree Marupalli… - Advanced Synthesis …, 2023 - Wiley Online Library
Visible‐light‐induced mild, transition metal, base, and photocatalyst‐free green protocol has
been developed for the synthesis of tryptanthrin and its derivatives. The present reaction is …
been developed for the synthesis of tryptanthrin and its derivatives. The present reaction is …
Visible Light‐Induced Radical‐Radical Coupling: One‐Pot Synthesis of 6‐Benzyl‐6‐hydroxyindolo[2,1‐b]quinazolin‐12(6H)‐ones from Isatins and Potassium …
LQ Huang, CL Dong, YH He… - Advanced Synthesis & …, 2022 - Wiley Online Library
A method for one‐pot synthesis of 6‐benzyl‐6‐hydroxyindolo [2, 1‐b] quinazolin‐12 (6H)‐
ones from isatins and potassium benzyl trifluoroborates was developed. Bioactive …
ones from isatins and potassium benzyl trifluoroborates was developed. Bioactive …
Discovery and Mechanism of Novel 7-Aliphatic Amine Tryptanthrin Derivatives against Phytopathogenic Bacteria
X Long, G Zhang, H Long, Q Wang, C Wang… - International Journal of …, 2023 - mdpi.com
Rice bacterial leaf blight is a destructive bacterial disease caused by Xanthomonas oryzae
pv. oryzae (Xoo) that seriously threatens crop yields and their associated economic benefits …
pv. oryzae (Xoo) that seriously threatens crop yields and their associated economic benefits …
Copper (I)-catalyzed synthesis of natural alkaloid tryptanthrin and its derivatives
J Hong, M Zhang, L Shi, P Liu, Y Guo, T Zhao… - New Journal of …, 2022 - pubs.rsc.org
A mild method for the preparation of tryptanthrin and its derivatives by copper (I) catalysis
with two identical isatins in the presence of KHCO3 as a base is described. Furthermore …
with two identical isatins in the presence of KHCO3 as a base is described. Furthermore …
Iodine-promoted amide formation via oxidative cleavage of indoles: novel quinazoline-4 (3 H)-one and tryptanthrin syntheses
A highly efficient method for the direct construction of amide bonds via a selective cleavage
of C–H and CC bonds in indole structures using an iodine-promoted approach was …
of C–H and CC bonds in indole structures using an iodine-promoted approach was …
Synthesis of pyrimidine-containing alkaloids
GY Remennikov - The Alkaloids: Chemistry and Biology, 2022 - Elsevier
This review deals with the synthesis of naturally occurring alkaloids containing partially or
completely saturated pyrimidine nuclei. The interest in these compounds is associated with …
completely saturated pyrimidine nuclei. The interest in these compounds is associated with …