New epilepsy therapies in development

P Klein, RM Kaminski, M Koepp… - Nature Reviews Drug …, 2024 - nature.com
Epilepsy is a common brain disorder, characterized by spontaneous recurrent seizures, with
associated neuropsychiatric and cognitive comorbidities and increased mortality. Although …

Fabrication of high-density out-of-plane microneedle arrays with various heights and diverse cross-sectional shapes

H Roh, YJ Yoon, JS Park, DH Kang, SM Kwak… - Nano-Micro Letters, 2022 - Springer
Out-of-plane microneedle structures are widely used in various applications such as
transcutaneous drug delivery and neural signal recording for brain machine interface. This …

[HTML][HTML] Hydrogel for light delivery in biomedical applications

PYM Yew, PL Chee, Q Lin, C Owh, J Li, QQ Dou… - Bioactive Materials, 2024 - Elsevier
Traditional optical waveguides or mediums are often silica-based materials, but their
applications in biomedicine and healthcare are limited due to the poor biocompatibility and …

A pH-sensitive closed-loop nanomachine to control hyperexcitability at the single neuron level

A Merolla, C Michetti, M Moschetta, F Vacca… - Nature …, 2024 - nature.com
Epilepsy affects 1% of the general population and 30% of patients are resistant to
antiepileptic drugs. Although optogenetics is an efficient antiepileptic strategy, the difficulty of …

Controllable Light Scattering on Fiber Bragg Gratings in Multimode Fibers: Tailoring Angular Emission for Advanced Fiber-Based Light Sources

A Reupert, I Chiamenti, M Chernysheva… - ACS …, 2023 - ACS Publications
We study lateral light scattering on fiber Bragg gratings (FBG) with the goal of creating an
optical fiber-based linear light source with controllable emission angles. The scattering from …

Quantitative analysis of the optogenetic excitability of CA1 neurons

R Schoeters, T Tarnaud, L Weyn, W Joseph… - Frontiers in …, 2023 - frontiersin.org
Introduction Optogenetics has emerged as a promising technique for modulating neuronal
activity and holds potential for the treatment of neurological disorders such as temporal lobe …

Radiation from Side‐Emitting Optical Fibers and Fiber Fabrics: Radiometric Model and Experimental Validation

A Reupert, J Schröder… - Advanced Photonics …, 2022 - Wiley Online Library
Side‐emitting optical fibers are diffuse light sources that emit guided light through their
cladding. Herein, two models to predict the generated radiation field are derived: one for the …

Advancements in non-invasive microwave brain stimulation: A comprehensive survey

FES Pereira, SK Jagatheesaperumal, SR Benjamin… - Physics of Life …, 2024 - Elsevier
This survey provides a comprehensive insight into the world of non-invasive brain
stimulation and focuses on the evolving landscape of deep brain stim-ulation through …

Investigating the Nucleation of AlOx and HfOx ALD on Polyimide: Influence of Plasma Activation

L Astoreca, D Schaubroeck, PS Esbah Tabaei… - Coatings, 2021 - mdpi.com
There is an increasing interest in atomic layer deposition (ALD) on polymers for the
development of membranes, electronics,(3D) nanostructures and specially for the …

Side-emitting fibers: targeted light scattering in optical fibers

A Reupert - 2022 - db-thueringen.de
Light scattering in optical fibers can transform the fiber into a linear light source with
customizable emission properties: a side-emitting fiber. Side-emitting fibers are light sources …