Graft-versus-host disease (GVHD) after allogeneic hematopoietic cell transplantation (HCT)
is associated with considerable morbidity and mortality, particularly in patients who do not …

Anti–T cell globulin (ATG) is polyclonal IgG from rabbits immunized with human thymocytes
or a human T cell line. Prophylaxis using ATG infused with conditioning for adult marrow or …

Graft failure may contribute to increased morbidity and mortality after allogeneic
hematopoietic SCT (allo-HSCT). Here, we present risk factors for graft failure in all first allo …

Seven patients underwent treatment with mesenchymal stem cells (MSCs), together with
allogeneic hematopoietic stem cell transplantation (HSCT). MSCs were given to three …

Mesenchymal stem cells (MSC) possess anti-inflammatory properties and participate in
tissue repair. We used MSC to heal therapy-induced tissue toxicity. Ten consecutive …

Do some patients benefit from an unrelated donor (URD) transplant because of a stronger
graft-versus-leukemia (GVL) effect? We analyzed 4099 patients with acute myeloid leukemia …

To evaluate the effect of the different doses of antithymocyte globulin (ATG) on the incidence
of acute GVHD among patients receiving hematopoietic SCT without ex vivo T-cell-depletion …

Allogeneic hematopoietic stem cell transplantation (alloHSCT) is increasingly being used for
treatment of hematologic malignancies, and the immunologic graft-versus-tumor effect (GVT) …

Abstract Background and Objectives To prevent graft-versus-host disease and rejection in
hematopoietic cell transplantation (HCT), children receive Thymoglobulin®, a polyclonal …

Background The optimal dose of rabbit antithymocyte globulin (ATG, ImtixSangstat)
minimizing infections without increasing graft-versus-host disease (GVHD) is unknown in T …