Endothelial cells that line capillaries are not just passive conduits for delivering blood.
Tissue-specific endothelium establishes specialized vascular niches that deploy sets of …

The repair of large bone defects remains a major clinical orthopaedic challenge. Bone is a
highly vascularised tissue reliant on the close spatial and temporal connection between …

An effective nanotherapeutic transport from the vasculature to the tumour is crucial for
cancer treatment with minimal side effects. Here we demonstrate that, in addition to the …

The precise mechanisms whereby anti-angiogenesis therapy blocks tumour growth or
causes vascular toxicity are unknown. We propose that endothelial cells establish a vascular …

We show that endothelial cell (EC)–generated vascular guidance tunnels (ie, matrix spaces
created during tube formation) serve as conduits for the recruitment and motility of pericytes …

We review the morphofunctional characteristics of pericytes and report our observations.
After a brief historical background, we consider the following aspects of pericytes: A) Origin …

The corneal epithelial basement membrane (BM) is positioned between basal epithelial
cells and the stroma. This highly specialized extracellular matrix functions not only to anchor …

Type 1 diabetes mellitus (T1DM) is a chronic metabolic disease caused by the destruction of
pancreatic β‐cells in response to autoimmune reactions. Shapiro et al. conducted novel islet …

The progressive loss of pancreatic β‐cell mass that occurs in both type 1 and type 2
diabetes is a primary factor driving efforts to identify strategies for effectively increasing …

Mammalian spermatogenesis produces numerous sperm for a long period based on a
highly potent stem cell system, which relies on a special microenvironment, or niche, that …