Akt (protein kinase B) is a serine/threonine protein kinase that regulates cell metabolism,
survival and proliferation. Recent studies of the role of Akt in phagocytosis, intracellular …

Background: Several clinically used COX-1 and COX-2 inhibitor drugs were reported to
possess severe side effects like GI ulcers and cardiovascular disturbances, respectively …

Background: Cardiovascular disease (CVD) remains the leading cause of global death, with
atherosclerosis being a major contributor to this mortality. Several mechanisms are …

Ethnopharmacological relevance Aralia, which belongs to Araliaceae family, is mainly
distributed in Asia, such as China, Japan and South Korea. It has a long medicinal history …

Pimaradienoic acid (PA; ent-pimara-8 (14), 15-dien-19-oic acid) is a pimarane diterpene
found in plants such as Vigueira arenaria Baker (Asteraceae) in the Brazilian savannas …

Sulforaphane (SFN), mainly derived from cruciferous vegetables, has received much
attention for its cancer chemopreventive property. Though there have been a few …

To assess the anti-inflammatory activity of the constituents of the roots of Aralia continentalis,
ent-pimara-8 (14), 15-diene-19-oic acid (continentalic acid, pimaradienoic acid, compound …

Ethno-pharmacological relevance The P. pinaster species, known as 'Pino nigral or rodeno',
is used in the treatment of colds, asthma, flu, and tuberculosis. Aim of the study This study …

Abstract A drimane,(+)-drimenol (1), five known herbertanes,(−)-α-herbertenol (2),(−)-
herbertenediol (3), mastigophorene A (4),(−)-mastigophorene C (5) and (−)-mastigophorene …

The genus Aralia contains many plants used medicinally in Asia and the Americas. Although
many members of this genus are used medicinally, the vast majority of this genus has not …