A comparative view of metabolite and substrate stress and tolerance in microbial bioprocessing: from biofuels and chemicals, to biocatalysis and bioremediation
SA Nicolaou, SM Gaida, ET Papoutsakis - Metabolic engineering, 2010 - Elsevier
Metabolites, substrates and substrate impurities may be toxic to cells by damaging biological
molecules, organelles, membranes or disrupting biological processes. Chemical stress is …
molecules, organelles, membranes or disrupting biological processes. Chemical stress is …
Transcriptional regulation of nonfermentable carbon utilization in budding yeast
B Turcotte, XB Liang, F Robert… - FEMS yeast …, 2009 - academic.oup.com
Saccharomyces cerevisiae preferentially uses glucose as a carbon source, but following its
depletion, it can utilize a wide variety of other carbons including nonfermentable compounds …
depletion, it can utilize a wide variety of other carbons including nonfermentable compounds …
Fatty acids production from hydrogen and carbon dioxide by mixed culture in the membrane biofilm reactor
Gasification of waste to syngas (H 2/CO 2) is seen as a promising route to a circular
economy. Biological conversion of the gaseous compounds into a liquid fuel or chemical …
economy. Biological conversion of the gaseous compounds into a liquid fuel or chemical …
Synthetic Biology of Cannabinoids and Cannabinoid Glucosides in Nicotiana benthamiana and Saccharomyces cerevisiae
T Gülck, JK Booth, Â Carvalho… - Journal of Natural …, 2020 - ACS Publications
Phytocannabinoids are a group of plant-derived metabolites that display a wide range of
psychoactive as well as health-promoting effects. The production of pharmaceutically …
psychoactive as well as health-promoting effects. The production of pharmaceutically …
The Path to Triacylglyceride Obesity in the sta6 Strain of Chlamydomonas reinhardtii
When the sta6 (starch-null) strain of the green microalga Chlamydomonas reinhardtii is
nitrogen starved in acetate and then “boosted” after 2 days with additional acetate, the cells …
nitrogen starved in acetate and then “boosted” after 2 days with additional acetate, the cells …
[HTML][HTML] Mechanisms underlying lactic acid tolerance and its influence on lactic acid production in Saccharomyces cerevisiae
A Peetermans, MR Foulquié-Moreno… - Microbial Cell, 2021 - ncbi.nlm.nih.gov
One of the major bottlenecks in lactic acid production using microbial fermentation is the
detrimental influence lactic acid accumulation poses on the lactic acid producing cells. The …
detrimental influence lactic acid accumulation poses on the lactic acid producing cells. The …
Quantitative analysis of the modes of growth inhibition by weak organic acids in Saccharomyces cerevisiae
Weak organic acids are naturally occurring compounds that are commercially used as
preservatives in the food and beverage industries. They extend the shelf life of food products …
preservatives in the food and beverage industries. They extend the shelf life of food products …
Adaptive laboratory evolution of tolerance to dicarboxylic acids in Saccharomyces cerevisiae
Improving the growth phenotypes of microbes in high product concentrations is an essential
design objective in the development of robust cell factories. However, the limited knowledge …
design objective in the development of robust cell factories. However, the limited knowledge …
Recent advances and challenges in the bioconversion of acetate to value-added chemicals
Acetate is a major byproduct of the bioconversion of the greenhouse gas carbon dioxide,
pretreatment of lignocellulose biomass, and microbial fermentation. The utilization and …
pretreatment of lignocellulose biomass, and microbial fermentation. The utilization and …
Metabolic engineering of Saccharomyces cerevisiae for production of carboxylic acids: current status and challenges
To meet the demands of future generations for chemicals and energy and to reduce the
environmental footprint of the chemical industry, alternatives for petrochemistry are required …
environmental footprint of the chemical industry, alternatives for petrochemistry are required …