It has become clear that the role of centrosomes extends well beyond that of important
microtubule organizers. There is increasing evidence that they also function as coordination …

Cilia play many essential roles in fluid transport and cellular locomotion, and as sensory
hubs for a variety of signal transduction pathways. Despite having a conserved basic …

Centrioles are 9-fold symmetrical structures at the core of centrosomes and base of cilia
whose dysfunction has been linked to a wide range of inherited diseases and cancer [1] …

The centrosome, a key microtubule organizing centre, is composed of centrioles, embedded
in a protein-rich matrix. Centrosomes control the internal spatial organization of somatic …

Microcephaly or reduced head circumference results from a multitude of abnormal
developmental processes affecting brain growth and/or leading to brain atrophy. Autosomal …

Centrioles are among the largest protein-based structures found in most cell types,
measuring approximately 250 nm in diameter and approximately 500 nm long in vertebrate …

Centrosomes organize microtubule (MT) arrays and are comprised of centrioles surrounded
by ordered pericentriolar proteins [1–4]. Centrioles are barrel-shaped structures composed …

Centrioles are required to assemble centrosomes for cell division and cilia for motility and
signalling. New centrioles assemble perpendicularly to pre-existing ones in G1–S and …

Centrioles are cylindrical structures that are usually composed of nine triplets of
microtubules (MTs) organized around a cartwheel‐shaped structure. Recent studies have …

The centriole organelle consists of microtubules (MTs) that exhibit a striking 9-fold radial
symmetry. Centrioles play fundamental roles across eukaryotes, notably in cell signaling …