Ki-67 protein as a tumour proliferation marker
SS Menon, C Guruvayoorappan, KM Sakthivel… - Clinica chimica acta, 2019 - Elsevier
Newer treatment strategy based on proliferative nuclear marker Ki-67 targeted therapy holds
promise for prioritized/personalized treatment options with regard to improved survival and …
promise for prioritized/personalized treatment options with regard to improved survival and …
Ki67 is a promising molecular target in the diagnosis of cancer
LT Li, G Jiang, Q Chen… - Molecular medicine …, 2015 - spandidos-publications.com
The expression of Ki67 is strongly associated with tumor cell proliferation and growth, and is
widely used in routine pathological investigation as a proliferation marker. The nuclear …
widely used in routine pathological investigation as a proliferation marker. The nuclear …
Ki67 is a graded rather than a binary marker of proliferation versus quiescence
Ki67 staining is widely used as a proliferation indicator in the clinic, despite poor
understanding of this protein's function or dynamics. Here, we track Ki67 levels under …
understanding of this protein's function or dynamics. Here, we track Ki67 levels under …
Cell-cycle regulation accounts for variability in Ki-67 expression levels
The cell proliferation antigen Ki-67 is widely used in cancer histopathology, but estimations
of Ki-67 expression levels are inconsistent and understanding of its regulation is limited …
of Ki-67 expression levels are inconsistent and understanding of its regulation is limited …
The cell proliferation antigen Ki-67 organises heterochromatin
Antigen Ki-67 is a nuclear protein expressed in proliferating mammalian cells. It is widely
used in cancer histopathology but its functions remain unclear. Here, we show that Ki-67 …
used in cancer histopathology but its functions remain unclear. Here, we show that Ki-67 …
Ki67 in breast cancer: prognostic and predictive potential
R Yerushalmi, R Woods, PM Ravdin, MM Hayes… - The lancet …, 2010 - thelancet.com
The leading parameters that define treatment recommendations in early breast cancer are
oestrogen-receptor, progesterone-receptor, and human epidermal growth-factor status …
oestrogen-receptor, progesterone-receptor, and human epidermal growth-factor status …
Ki-67 as a prognostic biomarker in invasive breast cancer
Simple Summary In breast cancer development, the expression of Ki-67 is strongly
associated with cancer proliferation and is a known indicator of prognosis and outcome. Ki …
associated with cancer proliferation and is a known indicator of prognosis and outcome. Ki …
Physiological functions and roles in cancer of the proliferation marker Ki-67
N Andrés-Sánchez, D Fisher… - Journal of Cell …, 2022 - journals.biologists.com
What do we know about Ki-67, apart from its usefulness as a cell proliferation biomarker in
histopathology? Discovered in 1983, the protein and its regulation of expression and …
histopathology? Discovered in 1983, the protein and its regulation of expression and …
Ki-67 regulates global gene expression and promotes sequential stages of carcinogenesis
K Mrouj, N Andrés-Sánchez, G Dubra… - Proceedings of the …, 2021 - National Acad Sciences
Ki-67 is a nuclear protein that is expressed in all proliferating vertebrate cells. Here, we
demonstrate that, although Ki-67 is not required for cell proliferation, its genetic ablation …
demonstrate that, although Ki-67 is not required for cell proliferation, its genetic ablation …
Neither soyfoods nor isoflavones warrant classification as endocrine disruptors: a technical review of the observational and clinical data
M Messina, SB Mejia, A Cassidy… - Critical Reviews in …, 2022 - Taylor & Francis
Soybeans are a rich source of isoflavones, which are classified as phytoestrogens. Despite
numerous proposed benefits, isoflavones are often classified as endocrine disruptors, based …
numerous proposed benefits, isoflavones are often classified as endocrine disruptors, based …