The sirtuin family in health and disease
QJ Wu, TN Zhang, HH Chen, XF Yu, JL Lv… - … and Targeted Therapy, 2022 - nature.com
Sirtuins (SIRTs) are nicotine adenine dinucleotide (+)-dependent histone deacetylases
regulating critical signaling pathways in prokaryotes and eukaryotes, and are involved in …
regulating critical signaling pathways in prokaryotes and eukaryotes, and are involved in …
The Lancet NCDI Poverty Commission: bridging a gap in universal health coverage for the poorest billion
Executive summary “As we embark on this great collective journey, we pledge that no one
will be left behind. Recognizing that the dignity of the human person is fundamental, we wish …
will be left behind. Recognizing that the dignity of the human person is fundamental, we wish …
Global epidemiology and outcomes of acute kidney injury
Acute kidney injury (AKI) is a commonly encountered syndrome associated with various
aetiologies and pathophysiological processes leading to decreased kidney function. In …
aetiologies and pathophysiological processes leading to decreased kidney function. In …
Single-nuclear transcriptomics reveals diversity of proximal tubule cell states in a dynamic response to acute kidney injury
LMS Gerhardt, J Liu, K Koppitch… - Proceedings of the …, 2021 - National Acad Sciences
Acute kidney injury (AKI), commonly caused by ischemia, sepsis, or nephrotoxic insult, is
associated with increased mortality and a heightened risk of chronic kidney disease (CKD) …
associated with increased mortality and a heightened risk of chronic kidney disease (CKD) …
[HTML][HTML] The global burden of kidney disease and the sustainable development goals
Kidney disease has been described as the most neglected chronic disease. Reliable
estimates of the global burden of kidney disease require more population-based studies, but …
estimates of the global burden of kidney disease require more population-based studies, but …
Catalytic activity tunable ceria nanoparticles prevent chemotherapy-induced acute kidney injury without interference with chemotherapeutics
Acute kidney injury (AKI) is a prevalent and lethal adverse event that severely affects cancer
patients receiving chemotherapy. It is correlated with the collateral damage to renal cells …
patients receiving chemotherapy. It is correlated with the collateral damage to renal cells …
[HTML][HTML] Timing of renal-replacement therapy in patients with acute kidney injury and sepsis
SD Barbar, R Clere-Jehl, A Bourredjem… - … England Journal of …, 2018 - Mass Medical Soc
Background Acute kidney injury is the most frequent complication in patients with septic
shock and is an independent risk factor for death. Although renal-replacement therapy is the …
shock and is an independent risk factor for death. Although renal-replacement therapy is the …
Global kidney health 2017 and beyond: a roadmap for closing gaps in care, research, and policy
The global nephrology community recognises the need for a cohesive plan to address the
problem of chronic kidney disease (CKD). In July, 2016, the International Society of …
problem of chronic kidney disease (CKD). In July, 2016, the International Society of …
[HTML][HTML] Controversies in acute kidney injury: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Conference
In 2012, Kidney Disease: Improving Global Outcomes (KDIGO) published a guideline on the
classification and management of acute kidney injury (AKI). The guideline was derived from …
classification and management of acute kidney injury (AKI). The guideline was derived from …
Creatinine: from physiology to clinical application
K Kashani, MH Rosner, M Ostermann - European journal of internal …, 2020 - Elsevier
Estimating static kidney function accurately and detecting changes in kidney function in a
timely fashion are challenging but critically important tasks. Serum creatinine is the most …
timely fashion are challenging but critically important tasks. Serum creatinine is the most …