Despite the prevalence of antisense transcripts in bacterial transcriptomes, little is known
about how their synthesis is controlled. We report that a major function of the Escherichia …

Genome-wide expression studies transformed the field of transcriptomics and made it
feasible to study global gene expression in extraordinary detail. These new methods have …

Genomic tiling array transcriptomics and RNA-seq are two powerful and rapidly developing
approaches for unbiased transcriptome analysis. Providing comprehensive identification …

Cellulosic biomass is an abundant and underused substrate for biofuel production. The
inability of many microbes to metabolize the pentose sugars abundant within hemicellulose …

We examine how different transcriptional network structures can evolve from an ancestral
network. By characterizing how the ancestral mode of gene regulation for genes specific to a …

In bacteria, translation-transcription coupling inhibits RNA polymerase (RNAP) stalling. We
present evidence suggesting that, upon amino acid starvation, inactive ribosomes promote …

Primary Examiner Frank W Lu (57) ABSTRACT Systems and methods for nucleic acid
sequencing are pro vided. Nucleic acid is fixed in double-stranded linearized stretched form …

Numerous thiol‐reactive compounds cause oxidative stress where cells counteract by
activation of survival strategies regulated by thiol‐based sensors. In Streptomyces …

Lignocellulosic plant material is a viable source of biomass to produce alternative energy
including ethanol and other biofuels. However, several factors—including toxic byproducts …

Abstract Background Dickeya dadantii and Pectobacterium atrosepticum are
phytopathogenic enterobacteria capable of facultative anaerobic growth in a wide range of …