Chemicals used for the induction of Alzheimer's disease-like cognitive dysfunctions in rodents

O Mahdi, MTH Baharuldin, NHM Nor… - Biomedical Research …, 2019 - biomedpress.org
Alzheimer's disease (AD) is the most frequent and multifactorial form of dementia,
characterised by multiple cognitive impairments and personality changes. Different methods …

Etiology and management of Alzheimer's disease: Potential role of gut microbiota modulation with probiotics supplementation

V Lekchand Dasriya, M Samtiya… - Journal of food …, 2022 - Wiley Online Library
Alzheimer's disease (AD) is the leading type of dementia in aging people and is a
progressive condition that causes neurodegeneration, resulting in confusion, memory loss …

Acetaminophen attenuates lipopolysaccharide-induced cognitive impairment through antioxidant activity

WX Zhao, JH Zhang, JB Cao, W Wang… - Journal of …, 2017 - Springer
Background Considerable evidence has shown that neuroinflammation and oxidative stress
play an important role in the pathophysiology of postoperative cognitive dysfunction (POCD) …

Dual role of vitamin C on the neuroinflammation mediated neurodegeneration and memory impairments in colchicine induced rat model of Alzheimer disease

S Sil, T Ghosh, P Gupta, R Ghosh, SN Kabir… - Journal of Molecular …, 2016 - Springer
The neurodegeneration in colchicine induced AD rats (cAD) is mediated by cox-2 linked
neuroinflammation. The importance of ROS in the inflammatory process in cAD has not been …

Role of cox-2 mediated neuroinflammation on the neurodegeneration and cognitive impairments in colchicine induced rat model of Alzheimer's Disease

S Sil, T Ghosh - Journal of neuroimmunology, 2016 - Elsevier
The neurodegeneration in colchicine induced AD (cAD) rats is linked with
neuroinflammation. The inducible cox-2 present in the brain may participate in the …

Paracetamol− Effect of early exposure on neurotransmission, spatial memory and motor performance in rats

K Blecharz-Klin, A Piechal, K Jawna-Zboińska… - Behavioural Brain …, 2017 - Elsevier
In the present study we examined the effect of prenatal and early life paracetamol exposure
on neurotransmission and its behavioural manifestation in rat male pups. In order to assess …

Long-term paracetamol treatment impairs cognitive function and brain-derived neurotrophic factor in adult rat brain

L Lalert, N Tantarungsee, T Chotipinit, W Ji-au… - Scientia …, 2023 - mdpi.com
Paracetamol (acetaminophen, APAP) is known as a safe pain reliever; however, its negative
effects on the central nervous system have gradually been reported. We examined …

Evaluation of neuroprotective effect of quercetin with donepezil in scopolamine-induced amnesia in rats

LA Pattanashetti, AD Taranalli… - Indian Journal of …, 2017 - journals.lww.com
Objective: The objective of this study was to evaluate the neuroprotective effect of quercetin
with donepezil in scopolamine-induced amnesia in rats. Materials and Methods: Five groups …

[HTML][HTML] Neuroprotective and therapeutic effect of Cordyceps militaris on ischemia-induced neuronal death and cognitive impairments

YO Kim, HJ Kim, GM Abu-Taweel, J Oh… - Saudi journal of biological …, 2019 - Elsevier
Cordyceps militaris is a type of fungus consumed by people all over the world and renowned
for their nutritional benefits and herbal formulas to promote health and longevity. In the …

Paracetamol (acetaminophen) rescues cognitive decline, neuroinflammation and cytoskeletal alterations in a model of post-operative cognitive decline (POCD) in …

B Garrone, L Durando, J Prenderville, E Sokolowska… - Scientific Reports, 2021 - nature.com
Post-operative cognitive dysfunction (POCD) is a debilitating clinical phenomenon in elderly
patients. Management of pain in elderly is complicated because analgesic opiates elicit …