Molecular and cellular mechanisms underlying the pathogenesis of Alzheimer's disease
Alzheimer's disease (AD) is the most common neurodegenerative disorder seen in age-
dependent dementia. There is currently no effective treatment for AD, which may be …
dependent dementia. There is currently no effective treatment for AD, which may be …
Long-term cognitive impairment after acute respiratory distress syndrome: a review of clinical impact and pathophysiological mechanisms
C Sasannejad, EW Ely, S Lahiri - Critical care, 2019 - Springer
Acute respiratory distress syndrome (ARDS) survivors experience a high prevalence of
cognitive impairment with concomitantly impaired functional status and quality of life, often …
cognitive impairment with concomitantly impaired functional status and quality of life, often …
The role of NMDA receptors in Alzheimer's disease
J Liu, L Chang, Y Song, H Li, Y Wu - Frontiers in neuroscience, 2019 - frontiersin.org
In Alzheimer's disease (AD), early synaptic dysfunction is associated with the increased
oligomeric amyloid-beta peptide, which causes NMDAR-dependent synaptic depression …
oligomeric amyloid-beta peptide, which causes NMDAR-dependent synaptic depression …
Amyloid-beta: a crucial factor in Alzheimer's disease
S Sadigh-Eteghad, B Sabermarouf, A Majdi… - Medical principles and …, 2015 - karger.com
Alzheimer's disease (AD) is the most prevalent form of dementia which affects people older
than 60 years of age. In AD, the dysregulation of the amyloid-beta (Aβ) level leads to the …
than 60 years of age. In AD, the dysregulation of the amyloid-beta (Aβ) level leads to the …
Drugs in clinical trials for Alzheimer's disease: the major trends
SO Bachurin, EV Bovina… - Medicinal research …, 2017 - Wiley Online Library
Alzheimer's disease (AD) is characterized by a chronic and progressive neurodegenerative
process resulting from the intracellular and extracellular accumulation of fibrillary proteins …
process resulting from the intracellular and extracellular accumulation of fibrillary proteins …
Depression in neurodegenerative diseases: Common mechanisms and current treatment options
CPC Galts, LEB Bettio, DC Jewett, CC Yang… - Neuroscience & …, 2019 - Elsevier
Major depressive disorder (MDD) is a highly prevalent psychiatric disorder and a major
cause of disability worldwide. This neurological condition is commonly associated with …
cause of disability worldwide. This neurological condition is commonly associated with …
[HTML][HTML] Calcium signaling in Alzheimer's disease & therapies
Alzheimer's disease (AD) is the most common type of dementia and is characterized by the
accumulation of amyloid (Aβ) plaques and neurofibrillary tangles in the brain. Much attention …
accumulation of amyloid (Aβ) plaques and neurofibrillary tangles in the brain. Much attention …
Extrasynaptic NMDA receptor involvement in central nervous system disorders
MP Parsons, LA Raymond - Neuron, 2014 - cell.com
NMDA receptor (NMDAR)-induced excitotoxicity is thought to contribute to the cell death
associated with certain neurodegenerative diseases, stroke, epilepsy, and traumatic brain …
associated with certain neurodegenerative diseases, stroke, epilepsy, and traumatic brain …
Memantine for the treatment of dementia: a review on its current and future applications
J Folch, O Busquets, M Ettcheto… - Journal of …, 2018 - content.iospress.com
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the presence in
the brain of extracellular amyloid-protein (A) and intracellular neurofibrillary tangles …
the brain of extracellular amyloid-protein (A) and intracellular neurofibrillary tangles …