Obesity I: Overview and molecular and biochemical mechanisms
Obesity is a chronic, relapsing condition characterized by excess body fat. Its prevalence
has increased globally since the 1970s, and the number of obese and overweight people is …
has increased globally since the 1970s, and the number of obese and overweight people is …
Nanogels: Synthesis, properties, and recent biomedical applications
Nanogels, also termed hydrogel nanoparticles, have the properties and functions of both
nanomaterials and hydrogels. Till date, a considerable number of nanogels have been …
nanomaterials and hydrogels. Till date, a considerable number of nanogels have been …
Metabolic syndrome
SL Samson, AJ Garber - Endocrinology and Metabolism Clinics, 2014 - endo.theclinics.com
A medical syndrome is a clustering of clinical findings that occur together more often than
would be expected by chance. The constellation of components that make up the metabolic …
would be expected by chance. The constellation of components that make up the metabolic …
Intestinal barrier dysfunction links metabolic and inflammatory markers of aging to death in Drosophila
Aging is characterized by a growing risk of disease and death, yet the underlying
pathophysiology is poorly understood. Indeed, little is known about how the functional …
pathophysiology is poorly understood. Indeed, little is known about how the functional …
[HTML][HTML] SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome
MD Hirschey, T Shimazu, E Jing, CA Grueter… - Molecular cell, 2011 - cell.com
Acetylation is increasingly recognized as an important metabolic regulatory posttranslational
protein modification, yet the metabolic consequence of mitochondrial protein …
protein modification, yet the metabolic consequence of mitochondrial protein …
Genetic basis for sex differences in obesity and lipid metabolism
JC Link, K Reue - Annual review of nutrition, 2017 - annualreviews.org
Men and women exhibit significant differences in obesity, cardiovascular disease, and
diabetes. To provide better diagnosis and treatment for both sexes, it is important to identify …
diabetes. To provide better diagnosis and treatment for both sexes, it is important to identify …
[HTML][HTML] Sex differences in obesity, lipid metabolism, and inflammation—a role for the sex chromosomes?
T Zore, M Palafox, K Reue - Molecular metabolism, 2018 - Elsevier
Background Sex differences in obesity and related diseases are well established. Gonadal
hormones are a major determinant of these sex differences. However, sex differences in …
hormones are a major determinant of these sex differences. However, sex differences in …
What is metabolic syndrome, and why are children getting it?
R Weiss, AA Bremer, RH Lustig - … of the New York Academy of …, 2013 - Wiley Online Library
Metabolic syndrome comprises a cluster of cardiovascular risk factors (hypertension, altered
glucose metabolism, dyslipidemia, and abdominal obesity) that occur in obese children …
glucose metabolism, dyslipidemia, and abdominal obesity) that occur in obese children …
A high-sugar diet produces obesity and insulin resistance in wild-type Drosophila
L Palanker Musselman, JL Fink… - Disease models & …, 2011 - journals.biologists.com
SUMMARY Insulin-resistant,'type 2'diabetes (T2D) results from a complex interplay between
genes and environment. In particular, both caloric excess and obesity are strongly …
genes and environment. In particular, both caloric excess and obesity are strongly …
Genetic control of de novo lipogenesis: role in diet-induced obesity
MS Strable, JM Ntambi - Critical reviews in biochemistry and …, 2010 - Taylor & Francis
De novo lipogenesis (DNL) is a complex yet highly regulated metabolic pathway, and
transcription factors such as liver X receptor (LXR), sterol regulatory element-binding protein …
transcription factors such as liver X receptor (LXR), sterol regulatory element-binding protein …