Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel

H Döhner, E Estey, D Grimwade… - Blood, The Journal …, 2017 - ashpublications.org
The first edition of the European LeukemiaNet (ELN) recommendations for diagnosis and
management of acute myeloid leukemia (AML) in adults, published in 2010, has found …

Acute lymphoblastic leukemia in children

SP Hunger, CG Mullighan - New England Journal of Medicine, 2015 - Mass Medical Soc
Acute Lymphoblastic Leukemia in Children | New England Journal of Medicine Skip to main
content The New England Journal of Medicine homepage Advanced Search SEARCH …

Clinical evolution, genetic landscape and trajectories of clonal hematopoiesis in SAMD9/SAMD9L syndromes

SS Sahoo, VB Pastor, C Goodings, RK Voss… - Nature medicine, 2021 - nature.com
Abstract Germline SAMD9 and SAMD9L mutations (SAMD9/9L mut) predispose to
myelodysplastic syndromes (MDS) with propensity for somatic rescue. In this study, we …

Genetic basis of acute lymphoblastic leukemia

I Iacobucci, CG Mullighan - Journal of Clinical Oncology, 2017 - ascopubs.org
Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, and despite cure
rates exceeding 90% in children, it remains an important cause of morbidity and mortality in …

The genetics of myelodysplastic syndrome: from clonal haematopoiesis to secondary leukaemia

AS Sperling, CJ Gibson, BL Ebert - Nature Reviews Cancer, 2017 - nature.com
Myelodysplastic syndrome (MDS) is a clonal disease that arises from the expansion of
mutated haematopoietic stem cells. In a spectrum of myeloid disorders ranging from clonal …

Acute myeloid leukemia

H Döhner, DJ Weisdorf… - New England Journal of …, 2015 - Mass Medical Soc
Acute Myeloid Leukemia | New England Journal of Medicine Skip to main content The New
England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology …

Advances in germline predisposition to acute leukaemias and myeloid neoplasms

JM Klco, CG Mullighan - Nature Reviews Cancer, 2021 - nature.com
Although much work has focused on the elucidation of somatic alterations that drive the
development of acute leukaemias and other haematopoietic diseases, it has become …

New insights into the differentiation of megakaryocytes from hematopoietic progenitors

LJ Noetzli, SL French, KR Machlus - … , thrombosis, and vascular …, 2019 - Am Heart Assoc
Megakaryocytes are hematopoietic cells, which are responsible for the production of blood
platelets. The traditional view of megakaryopoiesis describes the cellular journey from …

OF THE WORLD HEALTH ORGANIZATION CLASSIFICATION OF TUMORS OF THE HEMATOPOIETIC AND LYMPHOID TISSUES

JK Choi, W Xiao, X Chen, S Loghavi… - Modern Pathology, 2024 - Elsevier
This manuscript represents a review of lymphoblastic leukemia/lymphoma (acute
lymphoblastic leukemia/lymphoblastic lymphoma), acute leukemias of ambiguous lineage …

Childhood cancer predisposition syndromes—a concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric …

T Ripperger, SS Bielack, A Borkhardt… - American journal of …, 2017 - Wiley Online Library
Heritable predisposition is an important cause of cancer in children and adolescents.
Although a large number of cancer predisposition genes and their associated syndromes …