Ecdysone Control of Developmental Transitions: Lessons from Drosophila Research
N Yamanaka, KF Rewitz… - Annual review of …, 2013 - annualreviews.org
The steroid hormone ecdysone is the central regulator of insect developmental transitions.
Recent new advances in our understanding of ecdysone action have relied heavily on the …
Recent new advances in our understanding of ecdysone action have relied heavily on the …
Improvement of phosphoproteome analyses using FAIMS and decision tree fragmentation. application to the insulin signaling pathway in Drosophila melanogaster S2 …
G Bridon, E Bonneil… - Journal of proteome …, 2012 - ACS Publications
This report examines the analytical benefits of high-field asymmetric waveform ion mobility
spectrometry (FAIMS) coupled to liquid chromatography mass spectrometry (LC–MS) for …
spectrometry (FAIMS) coupled to liquid chromatography mass spectrometry (LC–MS) for …
Inhibition of ERK‐MAP kinase signaling by RSK during Drosophila development
Although p90 ribosomal S6 kinase (RSK) is known as an important downstream effector of
the ribosomal protein S6 kinase/extracellular signal‐regulated kinase (Ras/ERK) pathway …
the ribosomal protein S6 kinase/extracellular signal‐regulated kinase (Ras/ERK) pathway …
MKP-3 Has Essential Roles as a Negative Regulator of the Ras/Mitogen-Activated Protein Kinase Pathway during Drosophila Development
Mitogen-activated protein kinase (MAPK) phosphatase 3 (MKP-3) is a well-known negative
regulator in the Ras/extracellular signal-regulated kinase (ERK)-MAPK signaling pathway …
regulator in the Ras/extracellular signal-regulated kinase (ERK)-MAPK signaling pathway …
Insulin delays the progression of Drosophila cells through G2/M by activating the dTOR/dRaptor complex
MYW Wu, M Cully, D Andersen, SJ Leevers - The EMBO Journal, 2007 - embopress.org
In Drosophila and mammals, insulin signalling can increase growth, progression through
G1/S, cell size and tissue size. Here, we analyse the way insulin affects cell size and cell …
G1/S, cell size and tissue size. Here, we analyse the way insulin affects cell size and cell …
[HTML][HTML] SLOB, a SLOWPOKE Channel Binding Protein, Regulates Insulin Pathway Signaling and Metabolism in Drosophila
AL Sheldon, J Zhang, H Fei, IB Levitan - PLoS One, 2011 - journals.plos.org
There is ample evidence that ion channel modulation by accessory proteins within a
macromolecular complex can regulate channel activity and thereby impact neuronal …
macromolecular complex can regulate channel activity and thereby impact neuronal …
Drosophila PI3 kinase and Akt involved in insulin-stimulated proliferation and ERK pathway activation in Schneider cells
We have characterized the role of Drosophila PI3K and AKT in ERK pathway activation
involving insulin-induced proliferation using Drosophila Schneider cells. After insulin …
involving insulin-induced proliferation using Drosophila Schneider cells. After insulin …
Myogenic differentiation of Drosophila Schneider cells by DNA double-strand break-inducing drugs
Drosophila melanogaster has been widely used as a model organism to study various
aspects of development. Apart from the whole Drosophila embryo, there are a number of …
aspects of development. Apart from the whole Drosophila embryo, there are a number of …
Regulation of Drosophila MKP‐3 by Drosophila ERK
DMKP‐3 is a Drosophila dual‐specificity phosphatase, which has high substrate specificity
for Drosophila extracellular signal‐regulated kinases (DERK). By in vitro reconstitution …
for Drosophila extracellular signal‐regulated kinases (DERK). By in vitro reconstitution …
Insulin reduces apoptosis and increases DNA synthesis and cell size via distinct signalling pathways in Drosophila Kc cells
G Bikopoulos, RB Ceddia, G Sweeney… - Cell …, 2004 - Wiley Online Library
During development of Drosophila, cell proliferation and size are known to be regulated by
insulin. Here we use Drosophila Kc cells to examine the molecular basis for the control of …
insulin. Here we use Drosophila Kc cells to examine the molecular basis for the control of …