Engineered multispecific antibodies and other multimeric proteins with asymmetrical CH2-CH3 region mutations
M Chiu, A Zwolak - US Patent 11,149,094, 2021 - Google Patents
US11149094B2 - Engineered multispecific antibodies and other multimeric proteins with
asymmetrical CH2-CH3 region mutations - Google Patents US11149094B2 - Engineered …
asymmetrical CH2-CH3 region mutations - Google Patents US11149094B2 - Engineered …
Cell culture medium and process for controlling α-amidation and/or C-terminal amino acid cleavage of polypeptides
TF Trcek - US Patent 10,196,601, 2019 - Google Patents
The present invention is related to a cell culture medium for reducing the C-terminal
heterogeneity of a polypeptide expressed in cell-culture, wherein the medium comprises at …
heterogeneity of a polypeptide expressed in cell-culture, wherein the medium comprises at …
Antibodies that specifically bind PD-1 and methods of use
Q Chen, S Cole, K Duffy, Y Guo, D Gardner… - US Patent …, 2021 - Google Patents
US10995149B2 - Antibodies that specifically bind PD-1 and methods of use - Google
Patents US10995149B2 - Antibodies that specifically bind PD-1 and methods of use …
Patents US10995149B2 - Antibodies that specifically bind PD-1 and methods of use …
Methods of enhancing the sialic acid content of a CHO-expressed recombinant glycoprotein
J Tian - US Patent 11,655,457, 2023 - Google Patents
In accordance with the present invention, CHO cells expressing a recombinant polypeptide
of interest are grown in media where the amino acids, vitamins, phosphate, lipids and/or …
of interest are grown in media where the amino acids, vitamins, phosphate, lipids and/or …
Bioengineered T cell mediated immunity, materials and other methods for modulating cluster of differentiation IV and/or VIII
R Ganesan, S Singh, IS Grewal… - US Patent 11,926,667, 2024 - Google Patents
Provided herein, in certain aspects, are antibodies that bind to CD8, as well as recombinant
cells containing the vectors, and compositions comprising the antibodies. Also provided …
cells containing the vectors, and compositions comprising the antibodies. Also provided …
Proteins comprising HLA-G antigen binding domains and their uses
N Obermajer, A Zwolak, S Laquerre… - US Patent …, 2023 - Google Patents
2021-09-20 Assigned to JANSSEN RESEARCH & DEVELOPMENT, LLC reassignment
JANSSEN RESEARCH & DEVELOPMENT, LLC ASSIGNMENT OF ASSIGNORS INTEREST …
JANSSEN RESEARCH & DEVELOPMENT, LLC ASSIGNMENT OF ASSIGNORS INTEREST …
Proteins comprising cd3 antigen binding domains and uses thereof
J Luo, R BRITTINGHAM, YI Fang, SR BRODEUR… - 2021 - Google Patents
WO2021240388A1 - Proteins comprising cd3 antigen binding domains and uses thereof -
Google Patents WO2021240388A1 - Proteins comprising cd3 antigen binding domains and …
Google Patents WO2021240388A1 - Proteins comprising cd3 antigen binding domains and …
Materials and methods for binding siglec-3/cd33
PJ DOONAN, R Ganesan, MG DEREBE… - 2021 - Google Patents
WO2021181366A1 - Materials and methods for binding siglec-3/cd33 - Google Patents
WO2021181366A1 - Materials and methods for binding siglec-3/cd33 - Google Patents …
WO2021181366A1 - Materials and methods for binding siglec-3/cd33 - Google Patents …
Antibodies that specifically bind PD-1 and methods of use
Q Chen, S Cole, K Duffy, Y Guo, D Gardner… - US Patent …, 2023 - Google Patents
US11746161B2 - Antibodies that specifically bind PD-1 and methods of use - Google
Patents US11746161B2 - Antibodies that specifically bind PD-1 and methods of use …
Patents US11746161B2 - Antibodies that specifically bind PD-1 and methods of use …
Materials and methods for improved single chain variable fragments
J Luo, L Boucher, M Feldkamp, M Diem… - US Patent …, 2023 - Google Patents
2. BACKGROUND Antigen binding single chain variable fragments (scFv) are modules that
can be utilized broadly as therapeutics, imaging agents, diagnostic agents or as portions of …
can be utilized broadly as therapeutics, imaging agents, diagnostic agents or as portions of …