The prospects of achieving regeneration in the central nervous system (CNS) have
changed, as most recent findings indicate that several species, including humans, can …

Alzheimer's disease (AD) is a neurodegenerative disorder, characterized histopathologically
by the extracellular deposition of β-amyloid peptide in senile plaques, as well as intracellular …

Our long-term goal is to develop an artificial implant as a conduit for axonal regeneration
after peripheral nerve injury. In this study, biodegradable, aligned poly-ε-caprolactone (PCL) …

Abstract Development of biosynthetic conduits carrying extracellular matrix molecules and
cell lines expressing neurotrophic growth factors represents a novel and promising strategy …

Both Schwann cells and olfactory ensheathing cells (OECs) create an environment
favorable to axon regeneration when transplanted into the damaged CNS. However …

Olfactory ensheathing cells (OECs) continuously support the regeneration of olfactory
receptor neurons (ORNs). In addition, OECs promote regeneration of neurons within the …

One of the main research strategies to improve treatment for spinal cord injury involves the
use of cell transplantation. This review looks at the advantages and possible caveats of …

Astrocytes undergo major phenotypic changes in response to injury and disease that directly
influence repair in the CNS, but the mechanisms involved are poorly understood. Previously …

Several studies have demonstrated the potential of olfactory ensheathing cells for the repair
of central and peripheral nerve injury. However, the majority of these studies have been …

Olfactory ensheathing cells (OECs) are unique glia found only in the olfactory system that
retain exceptional plasticity, and support olfactory neurogenesis and the re-targeting across …