[HTML][HTML] Evaluation of biological activity of natural compounds: current trends and methods
C Barba-Ostria, SE Carrera-Pacheco… - Molecules, 2022 - mdpi.com
Natural compounds have diverse structures and are present in different forms of life.
Metabolites such as tannins, anthocyanins, and alkaloids, among others, serve as a defense …
Metabolites such as tannins, anthocyanins, and alkaloids, among others, serve as a defense …
[HTML][HTML] Advanced optical imaging for the rational design of nanomedicines
Despite the enormous potential of nanomedicines to shape the future of medicine, their
clinical translation remains suboptimal. Translational challenges are present in every step of …
clinical translation remains suboptimal. Translational challenges are present in every step of …
[HTML][HTML] Drug toxicity assessment: cell proliferation versus cell death
EV Sazonova, MS Chesnokov, B Zhivotovsky… - Cell Death …, 2022 - nature.com
Abstract Analysis of the toxicity of chemotherapeutic drugs is one of the main tasks of clinical
pharmacology. Decreased viability of tumor cells may reflect two important physiological …
pharmacology. Decreased viability of tumor cells may reflect two important physiological …
[HTML][HTML] Anticancer effects with molecular docking confirmation of newly synthesized isatin sulfonamide molecular hybrid derivatives against hepatic cancer cell lines
The current study investigated the cytotoxic effect of ten sulfonamide-derived isatins,
following molecular hybridization, based on the association principles, on hepatocellular …
following molecular hybridization, based on the association principles, on hepatocellular …
[HTML][HTML] 3D bioprinting of polycaprolactone-based scaffolds for pulp-dentin regeneration: Investigation of physicochemical and biological behavior
In this study, two structurally different scaffolds, a polycaprolactone (PCL)/45S5 Bioglass
(BG) composite and PCL/hyaluronic acid (HyA) were fabricated by 3D printing technology …
(BG) composite and PCL/hyaluronic acid (HyA) were fabricated by 3D printing technology …
[HTML][HTML] Oxygen generating scaffolds regenerate critical size bone defects
Recent innovations in bone tissue engineering have introduced biomaterials that generate
oxygen to substitute vasculature. This strategy provides the immediate oxygen required for …
oxygen to substitute vasculature. This strategy provides the immediate oxygen required for …
[HTML][HTML] Nutritional Value and Biofunctionalities of Two Edible Green Seaweeds (Ulva lactuca and Caulerpa racemosa) from Indonesia by Subcritical Water …
Caulerpa racemosa (sea grapes) and Ulva lactuca (sea lettuces) are edible green
seaweeds and good sources of bioactive compounds for future foods, nutraceuticals and …
seaweeds and good sources of bioactive compounds for future foods, nutraceuticals and …
[HTML][HTML] Quercetin, rutin and quercetin-rutin incorporated hydroxypropyl β-cyclodextrin inclusion complexes
Quercetin (Q) and rutin (R) are well known and most studied flavonoids due to their activities
in reduction of inflammation, oxidative damage, platelet aggregation and inhibition of cancer …
in reduction of inflammation, oxidative damage, platelet aggregation and inhibition of cancer …
The efficient activity of plant essential oils for inhibiting Botrytis cinerea and Penicillium expansum: Mechanistic insights into antifungal activity
Botrytis cinerea and Penicillium expansum produce deterioration in fruit quality, causing
losses to the food industry. Thus, plant essential oils (EOs) have been proposed as a …
losses to the food industry. Thus, plant essential oils (EOs) have been proposed as a …
Thermosensitive in situ hydrogels of rivastigmine-loaded lipid-based nanosystems for nose-to-brain delivery: Characterisation, biocompatibility, and drug deposition …
S Cunha, M Swedrowska, Y Bellahnid, Z Xu… - International Journal of …, 2022 - Elsevier
Acetylcholinesterase inhibitors are the most used drugs to manage Alzheimer's disease,
although they show low bioavailability in the brain. In this sense, nasal administration has …
although they show low bioavailability in the brain. In this sense, nasal administration has …