Sofosbuvir and velpatasvir for HCV in patients with decompensated cirrhosis

MP Curry, JG O'Leary, N Bzowej, AJ Muir… - … England Journal of …, 2015 - Mass Medical Soc
Background As the population that is infected with the hepatitis C virus (HCV) ages, the
number of patients with decompensated cirrhosis is expected to increase. Methods We …

Hepatitis C virus therapy in advanced liver disease: outcomes and challenges

S Ekpanyapong, KR Reddy - United European …, 2019 - journals.sagepub.com
While for many years investigators had worked on highly effective direct-acting antiviral
agent (DAA) therapy, we are now encountering challenges on the appropriate timing of DAA …

Direct-acting antivirals for HCV treatment in decompensated liver cirrhosis patients: a systematic review and meta-analysis

JH An, DA Park, MJ Ko, SB Ahn, JJ Yoo… - Journal of Personalized …, 2022 - mdpi.com
DAA therapy is known to clear hepatitis C virus infection in patients with decompensated
cirrhosis (DC). However, the safety and benefits of DAA in DC remain unclear, especially …

Artificial intelligence predicts direct-acting antivirals failure among hepatitis C virus patients: A nationwide hepatitis C virus registry program

MY Lu, CF Huang, CH Hung, CM Tai… - Clinical and …, 2023 - pmc.ncbi.nlm.nih.gov
Background/Aims Despite the high efficacy of direct-acting antivirals (DAAs), approximately
1–3% of hepatitis C virus (HCV) patients fail to achieve a sustained virological response. We …

Effect of sofosbuvir-based hepatitis C virus therapy on kidney function in patients with CKD

ME Sise, E Backman, GA Ortiz… - Clinical Journal of the …, 2017 - journals.lww.com
Results Ninety-eight patients with CKD (42% stage 1 or 2 CKD and 58% stage 3 CKD) were
included. Mean age was 62 years old, 78% were men, and 65% were white. Additionally …

Lactic acidosis in patients with hepatitis C virus cirrhosis and combined ribavirin/sofosbuvir treatment

MW Welker, S Luhne, CM Lange, J Vermehren… - Journal of …, 2016 - Elsevier
Background & Aims Sofosbuvir (SOF) based interferon-alfa free antiviral therapy has
become the treatment of choice for patients with chronic hepatitis C virus (HCV) infection …

[PDF][PDF] Kronik hepatit B virusu infeksiyonunun yönetimi: Türk klinik mikrobiyoloji ve infeksiyon hastalıkları derneği viral hepatit çalışma grubu uzlaşı raporu

S Akhan, A Aynıoğlu, A Çağatay, İ Gönen, Ö Günal… - Klimik Derg, 2014 - klimikdergisi.org
Özet Türk Klinik Mikrobiyoloji ve İnfeksiyon Hastalıkları Derneği Viral Hepatit Çalışma Grubu,
dünyada 400 milyonun üzerinde kişide bulunan kronik hepatit B virusu (HBV) …

Incidence of DAA failure and the clinical impact of retreatment in real-life patients treated in the advanced stage of liver disease: Interim evaluations from the PITER …

LA Kondili, GB Gaeta, MR Brunetto, A Di Leo… - PLoS …, 2017 - journals.plos.org
Background Few data are available on the virological and clinical outcomes of advanced
liver disease patients retreated after first-line DAA failure. Aim To evaluate DAA failure …

[HTML][HTML] Hepatitis C virus and liver transplantation

KR Bhamidimarri, SK Satapathy… - Gastroenterology & …, 2017 - ncbi.nlm.nih.gov
Hepatitis C virus (HCV) is a major cause of death from infectious disease and is still the
leading indication for liver transplantation in the United States and other Western countries …

Model for end‐stage liver disease limbo, model for end‐stage liver disease purgatory, and the dilemma of treating hepatitis C in patients awaiting liver transplantation

AF Carrion, SA Khaderi, NL Sussman - Liver Transplantation, 2016 - journals.lww.com
The increasing effectiveness of oral regimens to treat hepatitis C has raised questions about
their role in treating patients with decompensated cirrhosis, especially those awaiting …