The discovery that dentine is a reservoir of bioactive molecules that can be recruited on
demand has attracted efforts to develop new protocols and materials for vital pulp therapy …

Adult stem cells research has been considered the most advanced sort of medical-scientific
research, particularly stem cells from human exfoliated deciduous teeth (SHED), which …

Maintaining dental pulp vitality and preventing tooth loss are two challenges in endodontic
treatment. A tooth lacking a viable pulp loses its defense mechanism and regenerative …

Background Stem cells from apical papilla (SCAP) are a subpopulation of mesenchymal
stem cells (MSCs) isolated from the apical papilla of the developing tooth root apex of …

Nuclear receptor peroxisome proliferator-activated receptor-γ (PPARγ) is an essential
transcription factor for adipocyte differentiation. In mesenchymal stem cells, PPARγ has …

Insight into the molecular mechanisms governing the development and maintenance of
pluripotency is important for understanding early development and the use of stem cells in …

Background Dental pulp stem cells (DPSCs) play a crucial role in dentin-pulp complex
regeneration. Further understanding of the mechanism by which DPSCs remain in a …

INTRODUCTION: MicroRNAs (miRNAs) play momentous roles in various biological
processes including cell differentiation. However, little is known about the role of miRNAs in …

The dental pulp, a non-mineralized connective tissue uniquely encased within the cavity of
the tooth, provides a niche for diverse arrays of dental mesenchymal stem cells. Stem cells …

Tooth-related diseases and tooth loss are widespread and are a major public health issue.
The loss of teeth can affect chewing, speech, appearance and even psychology. Therefore …