[HTML][HTML] The anatomy of apathy: a neurocognitive framework for amotivated behaviour

C Le Heron, MAJ Apps, M Husain - Neuropsychologia, 2018 - Elsevier
Apathy is a debilitating syndrome associated with many neurological disorders, including
several common neurodegenerative diseases such as Parkinson's disease and Alzheimer's …

Why not try harder? Computational approach to motivation deficits in neuro-psychiatric diseases

M Pessiglione, F Vinckier, S Bouret, J Daunizeau… - Brain, 2018 - academic.oup.com
Motivation deficits, such as apathy, are pervasive in both neurological and psychiatric
diseases. Even when they are not the core symptom, they reduce quality of life, compromise …

Neurocomputational mechanisms underlying subjective valuation of effort costs

TTJ Chong, M Apps, K Giehl, A Sillence, LL Grima… - PLoS …, 2017 - journals.plos.org
In everyday life, we have to decide whether it is worth exerting effort to obtain rewards. Effort
can be experienced in different domains, with some tasks requiring significant cognitive …

Motivational fatigue: A neurocognitive framework for the impact of effortful exertion on subsequent motivation

T Müller, MAJ Apps - Neuropsychologia, 2019 - Elsevier
Fatigue–a feeling of exhaustion arising from exertion–is a significant barrier to successful
behaviour and one of the most prominent symptoms in primary care. During extended …

Neural and computational mechanisms of momentary fatigue and persistence in effort-based choice

T Müller, MC Klein-Flügge, SG Manohar… - Nature …, 2021 - nature.com
From a gym workout, to deciding whether to persevere at work, many activities require us to
persist in deciding that rewards are 'worth the effort'even as we become fatigued. However …

Prosocial apathy for helping others when effort is required

PL Lockwood, M Hamonet, SH Zhang… - Nature human …, 2017 - nature.com
Prosocial acts—those that are costly to ourselves but benefit others—are a central
component of human coexistence–. While the financial and moral costs of prosocial …

Apathy but not diminished expression in schizophrenia is associated with discounting of monetary rewards by physical effort

MN Hartmann, OM Hager, AV Reimann… - Schizophrenia …, 2015 - academic.oup.com
Negative symptoms in schizophrenia have been grouped into the 2 factors of apathy and
diminished expression, which might be caused by separable pathophysiological …

Separate mesocortical and mesolimbic pathways encode effort and reward learning signals

TU Hauser, E Eldar, RJ Dolan - Proceedings of the …, 2017 - National Acad Sciences
Optimal decision making mandates organisms learn the relevant features of choice options.
Likewise, knowing how much effort we should expend can assume paramount importance …

Individual differences in premotor brain systems underlie behavioral apathy

V Bonnelle, S Manohar, T Behrens, M Husain - Cerebral cortex, 2016 - academic.oup.com
Lack of physical engagement, productivity, and initiative—so-called “behavioral apathy”—is
a common problem with significant impact, both personal and economic. Here, we …

The subjective value of cognitive effort is encoded by a domain-general valuation network

A Westbrook, B Lamichhane, T Braver - Journal of Neuroscience, 2019 - Soc Neuroscience
Cognitive control is necessary for goal-directed behavior, yet people treat cognitive control
demand as a cost, which discounts the value of rewards in a similar manner as other costs …