Apical periodontitis is a sequel to endodontic infection and manifests itself as the host
defense response to microbial challenge emanating from the root canal system. It is viewed …

Objectives This review article discusses the host response in apical periodontitis with the
main focus on cytokines, produced under this pathological condition and contributing to the …

Objective: To evaluate a possible association between wrist and periodontal destruction in
rheumatoid arthritis, and between periodontal destruction, dry mouth, and labial salivary …

The strict link between periodontitis (PD) and rheumatoid arthritis (RA) has been widely
demonstrated by several studies. PD is significantly more frequent in RA patients in …

Proinflammatory and immunoregulatory cytokines are important for the pathogenesis of
periapical lesions. However, little is known about how their functions are balanced and …

Streptococcus gordonii, a Gram-positive bacterium, is a commensal bacterium that is
commonly found in the skin, oral cavity, and intestine. It is also known as an opportunistic …

INTRODUCTION: The proinflammatory cytokine interleukin (IL)-1 is a key regulator of host
responses to microbial infection and a major modulator of extracellular matrix catabolism …

Abstract Abstract Wahlgren J, Salo T, Teronen O, Luoto H, Sorsa T, Tjäderhane. Matrix
metalloproteinase-8 (MMP-8) in pulpal and periapical inflammation and periapical root …

INTRODUCTION: Macrophages are highly activated by endodontic contents. This study
investigated the correlation between different clinical signs/symptoms and radiographic …

The development, establishment and repair of apical periodontitis (AP) is dependent of
several factors, which include host susceptibility, microbial infection, immune response …