Regeneration, the replacement of lost body parts, is widespread yet highly variable among
animals. Explaining this variation remains a major challenge in biology. Great strides have …

Although tremendous progress has been achieved in understanding the molecular basis of
tissue repair and regeneration in diverse model organisms, the tendency of mammals for …

Influx of macrophages plays a crucial role in tissue repair. However, the precise function of
macrophages during the healing response has remained a subject of debate due to their …

The regrowth of amputated limbs and the distal tips of digits represent models of tissue
regeneration in amphibians, fish and mice. For decades it had been assumed that limb …

How the immune system affects tissue regeneration is not well understood. In this study, we
used an emerging mammalian model of epimorphic regeneration, the African spiny mouse …

The tips of mammalian digits can regenerate after amputation,, like those of amphibians. It is
unknown why this capacity is limited to the area associated with the nail,,. Here we show that …

Studying regeneration in animals where and when it occurs is inherently interesting and a
challenging research topic within developmental biology. Historically, vertebrate …

The migration of cells from the side and the bottom of the defect is important in
osteochondral defect healing. Here, we designed a novel collagen scaffold that possessed …

Adult mammals have lost multi-tissue regenerative capacity, except for the distal digit, which
is able to regenerate via mechanisms that remain largely unknown. Here, we show that, after …

Regeneration of appendages is frequent among invertebrates as well as some vertebrates.
However, in mammals this has been largely relegated to digit tip regeneration, as found in …