The bone marrow niche has mystified scientists for many years, leading to widespread
investigation to shed light into its molecular and cellular composition. Considerable efforts …

Osteoporosis is a chronical, systemic skeletal disorder characterized by an increase in bone
resorption, which leads to reduced bone density. The reduction in bone mineral density and …

Bone marrow mesenchymal lineage cells are a heterogeneous cell population involved in
bone homeostasis and diseases such as osteoporosis. While it is long postulated that they …

The in vivo origin of bone-producing osteoblasts is not fully defined. Skeletal stem cells, a
population of mesenchymal stem cells resident in the bone marrow compartment, are …

Mesenchymal stem cells (MSCs) from bone marrow are main cell source for tissue repair
and engineering, and vehicles of cell-based gene therapy. Unlike other species, mouse …

Aim: We describe the minimum requirements and a simplified method for isolation and
characterization of mesenchymal stem cells (MSCs) from human bone marrow. Background …

The periosteum is the major source of cells involved in fracture healing. We sought to
characterize progenitor cells and their contribution to bone fracture healing. The periosteum …

Multipotent mesenchymal stromal cells (MSCs) are required for skeletal formation,
maintenance, and repair throughout life; however, current models posit that postnatally …

Bone marrow mesenchymal stem cells (BMSCs) exhibit an age-related lineage switch
between osteogenic and adipogenic fates, which contributes to bone loss and adiposity …

Focal radiotherapy is frequently associated with skeletal damage within the radiation field.
Our previous in vitro study showed that activation of Wnt/β‐catenin pathway can overcome …