Polycyclic aromatic hydrocarbons (PAHs) are organic compounds that are widely distributed
in the air, water, and soil. Recently, the amount of PAHs derived from fuels and from …

Vitamin D 3 is already found early in the evolution of life but essentially as inactive end
products of the photochemical reaction of 7-dehydrocholestol with ultraviolet light B. A full …

Fish, like mammals, have to maintain their body fluid ionic and osmotic homeostasis through
sophisticated iono-/osmoregulation mechanisms, which are conducted mainly by ionocytes …

Recent data suggest an increase in the overall incidence of parathyroid disorders, with
primary hyperparathyroidism (PHPT) being the most prevalent parathyroid disorder. PHPT is …

Exposure to the space environment induces a number of pathophysiological outcomes in
astronauts, including bone demineralization, sleep disorders, circadian clock dysregulation …

The identification of disease-causing mutations has in recent years progressed immensely
due to whole genome sequencing approaches using patient material. The task accordingly …

Differentiation of osteoclasts (OCs) from hematopoietic cells requires cellular interaction with
osteoblasts (OBs). Due to the difficulty of live-imaging in the bone, however, the cellular and …

Astronauts experience osteoporosis‐like loss of bone mass because of microgravity
conditions during space flight. To prevent bone loss, they need a riskless and antiresorptive …

Teleost fish such as zebrafish (Danio rerio) are increasingly used for physiological, genetic
and developmental studies. Our understanding of the physiological consequences of altered …

Estrogens play well-recognized roles in reproduction across vertebrates, but also intervene
in a wide range of other physiological processes, including mineral homeostasis. Classical …