Methotrexate: a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in rheumatoid arthritis and other immunoregulatory disorders

A Markham, D Faulds - Clinical Immunotherapeutics, 1994 - Springer
Synopsis Methotrexate is a folic acid antagonist which appears to have immunosuppressive
and/or anti-inflammatory effects. Many well-designed studies have shown that methotrexate …