Trithorax and Polycomb group-dependent regulation: a tale of opposing activities

SJ Geisler, R Paro - Development, 2015 - journals.biologists.com
Intricate layers of regulation determine the unique gene expression profiles of a given cell
and, therefore, underlie the immense phenotypic diversity observed among cell types …

[HTML][HTML] LncRNAs: key players and novel insights into diabetes mellitus

X He, C Ou, Y Xiao, Q Han, H Li, S Zhou - Oncotarget, 2017 - ncbi.nlm.nih.gov
Abstract Long non-coding RNAs (LncRNAs) are a class of endogenous RNA molecules,
which have a transcribing length of over 200 nt, lack a complete functional open reading …

Altered expression of the imprinted transcription factor PLAGL1 deregulates a network of genes in the human IUGR placenta

I Iglesias-Platas, A Martin-Trujillo… - Human molecular …, 2014 - academic.oup.com
Genomic imprinting is the epigenetic process that results in monoallelic expression of genes
depending on parental origin. These genes are known to be critical for placental …

Imprinted genes in mouse placental development and the regulation of fetal energy stores

SJ Tunster, AB Jensen, RM John - Reproduction, 2013 - rep.bioscientifica.com
Imprinted genes, which are preferentially expressed from one or other parental chromosome
as a consequence of epigenetic events in the germline, are known to functionally converge …

Dysregulation of the long non-coding RNA transcriptome in a Rett syndrome mouse model

P Petazzi, J Sandoval, K Szczesna, OC Jorge, L Roa… - RNA biology, 2013 - Taylor & Francis
Mecp2 is a transcriptional repressor protein that is mutated in Rett syndrome, a
neurodevelopmental disorder that is the second most common cause of mental retardation …

Genome‐wide allelic methylation analysis reveals disease‐specific susceptibility to multiple methylation defects in imprinting syndromes

F Court, A Martin‐Trujillo, V Romanelli, I Garin… - Human …, 2013 - Wiley Online Library
Genomic imprinting is the parent‐of‐origin‐specific allelic transcriptional silencing observed
in mammals, which is governed by DNA methylation established in the gametes and …

DNA methylation entropy is associated with DNA sequence features and developmental epigenetic divergence

Y Fang, Z Ji, W Zhou, J Abante… - Nucleic acids …, 2023 - academic.oup.com
Epigenetic information defines tissue identity and is largely inherited in development
through DNA methylation. While studied mostly for mean differences, methylation also …

High-resolution profiling of novel transcribed regions during rat spermatogenesis

F Chalmel, A Lardenois, B Evrard… - Biology of …, 2014 - academic.oup.com
Mammalian spermatogenesis is a complex and highly orchestrated combination of
processes in which male germline proliferation and differentiation result in the production of …

Longitudinal effects of developmental bisphenol A exposure on epigenome-wide DNA hydroxymethylation at imprinted loci in mouse blood

JJ Kochmanski, EH Marchlewicz… - Environmental …, 2018 - ehp.niehs.nih.gov
Background: Epigenetic machinery plays an important role in genomic imprinting, a
developmental process that establishes parent-of-origin–specific monoallelic gene …

Epigenetic heredity of human height

P Simeone, S Alberti - Physiological reports, 2014 - Wiley Online Library
Genome‐wide SNP analyses have identified genomic variants associated with adult human
height. However, these only explain a fraction of human height variation, suggesting that …