Trithorax and Polycomb group-dependent regulation: a tale of opposing activities
SJ Geisler, R Paro - Development, 2015 - journals.biologists.com
Intricate layers of regulation determine the unique gene expression profiles of a given cell
and, therefore, underlie the immense phenotypic diversity observed among cell types …
and, therefore, underlie the immense phenotypic diversity observed among cell types …
[HTML][HTML] LncRNAs: key players and novel insights into diabetes mellitus
X He, C Ou, Y Xiao, Q Han, H Li, S Zhou - Oncotarget, 2017 - ncbi.nlm.nih.gov
Abstract Long non-coding RNAs (LncRNAs) are a class of endogenous RNA molecules,
which have a transcribing length of over 200 nt, lack a complete functional open reading …
which have a transcribing length of over 200 nt, lack a complete functional open reading …
Altered expression of the imprinted transcription factor PLAGL1 deregulates a network of genes in the human IUGR placenta
I Iglesias-Platas, A Martin-Trujillo… - Human molecular …, 2014 - academic.oup.com
Genomic imprinting is the epigenetic process that results in monoallelic expression of genes
depending on parental origin. These genes are known to be critical for placental …
depending on parental origin. These genes are known to be critical for placental …
Imprinted genes in mouse placental development and the regulation of fetal energy stores
SJ Tunster, AB Jensen, RM John - Reproduction, 2013 - rep.bioscientifica.com
Imprinted genes, which are preferentially expressed from one or other parental chromosome
as a consequence of epigenetic events in the germline, are known to functionally converge …
as a consequence of epigenetic events in the germline, are known to functionally converge …
Dysregulation of the long non-coding RNA transcriptome in a Rett syndrome mouse model
Mecp2 is a transcriptional repressor protein that is mutated in Rett syndrome, a
neurodevelopmental disorder that is the second most common cause of mental retardation …
neurodevelopmental disorder that is the second most common cause of mental retardation …
Genome‐wide allelic methylation analysis reveals disease‐specific susceptibility to multiple methylation defects in imprinting syndromes
F Court, A Martin‐Trujillo, V Romanelli, I Garin… - Human …, 2013 - Wiley Online Library
Genomic imprinting is the parent‐of‐origin‐specific allelic transcriptional silencing observed
in mammals, which is governed by DNA methylation established in the gametes and …
in mammals, which is governed by DNA methylation established in the gametes and …
DNA methylation entropy is associated with DNA sequence features and developmental epigenetic divergence
Epigenetic information defines tissue identity and is largely inherited in development
through DNA methylation. While studied mostly for mean differences, methylation also …
through DNA methylation. While studied mostly for mean differences, methylation also …
High-resolution profiling of novel transcribed regions during rat spermatogenesis
F Chalmel, A Lardenois, B Evrard… - Biology of …, 2014 - academic.oup.com
Mammalian spermatogenesis is a complex and highly orchestrated combination of
processes in which male germline proliferation and differentiation result in the production of …
processes in which male germline proliferation and differentiation result in the production of …
Longitudinal effects of developmental bisphenol A exposure on epigenome-wide DNA hydroxymethylation at imprinted loci in mouse blood
JJ Kochmanski, EH Marchlewicz… - Environmental …, 2018 - ehp.niehs.nih.gov
Background: Epigenetic machinery plays an important role in genomic imprinting, a
developmental process that establishes parent-of-origin–specific monoallelic gene …
developmental process that establishes parent-of-origin–specific monoallelic gene …
Epigenetic heredity of human height
Genome‐wide SNP analyses have identified genomic variants associated with adult human
height. However, these only explain a fraction of human height variation, suggesting that …
height. However, these only explain a fraction of human height variation, suggesting that …