In vivo and in vitro models of hepatocellular carcinoma: current strategies for translational modeling

GR Romualdo, K Leroy, CJS Costa, GB Prata… - Cancers, 2021 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is a highly incident and deadly malignant
neoplasia, and only a few anti-HCC drugs are currently available. Thus, the development of …

Past, present, and future of chemically induced hepatocarcinogenesis rodent models: Perspectives concerning classic and new cancer hallmarks

GR Romualdo, R Heidor, GP Bacil, FS Moreno… - Life Sciences, 2023 - Elsevier
Hepatocellular carcinoma (HCC), the main primary liver cancer, accounts for 5% of all
incident cases and 8.4% of all cancer-related deaths worldwide. HCC displays a spectrum of …

Comparative analysis of traditional and modern fermentation for Xuecai and correlations between volatile flavor compounds and bacterial community

J Zhang, C Zhang, X Xin, D Liu, W Zhang - Frontiers in microbiology, 2021 - frontiersin.org
Differences in flavor compounds and bacterial communities of Xuecai by traditional and
modern fermentation are poorly understood. Allyl isothiocyanate (E9), ethyl acetate (E1), 3 …

Apocarotenoids from Equisetum debile Roxb. ex Vaucher regulate the lipid metabolism via the activation of the AMPK/ACC/SREBP-1c signaling pathway

Q Xu, W Tian, S He, M Zhou, Y Gao, X Liu, C Sun… - Bioorganic …, 2023 - Elsevier
Abstract Sixteen undescribed apocarotenoids (1–16), along with 22 known analogues, were
isolated from the aerial parts of Equisetum debile. Their structures, including absolute …

[HTML][HTML] Evaluation of antioxidant, antimicrobial, antidiabetic, anti-tyrosinase, and neuroprotective effects of β-ionone: in vitro and in silico analysis

J Touhtouh, M Laghmari, T Benali, T Aanniz… - Results in …, 2024 - Elsevier
Abstract β-Ionone is a bioactive phytochemical that has been extracted from many flowers,
vegetables, and fruits. β-Ionone is an intriguing lead molecule from which several …

[HTML][HTML] Using β-Elemene to reduce stemness and drug resistance in osteosarcoma: A focus on the AKT/FOXO1 signaling pathway and immune modulation

S Zhang, Z Xing, J Ke - Journal of Bone Oncology, 2024 - Elsevier
Objective Osteosarcoma, a highly malignant bone tumor, poses significant treatment
challenges due to its propensity for stemness and drug resistance, particularly against …

Mechanisms of hepatic cancer by persistent organic pollutants

JE Klaunig, L Melo, K Tilmant - Current Opinion in Toxicology, 2020 - Elsevier
Persistent organic pollutants (POPs) are a group of organic chemicals, as defined by the
Stockholm Convention that are persistent in the environment and accumulate in organisms …

[PDF][PDF] Aktywność biologiczna wybranych składników olejków eterycznych. Cz. 2

K Antoniak, W Bylka - Post. Fitoter, 2020 - postepyfitoterapii.pl
Olejki eteryczne są mieszaninami wielu związków, głównie terpenów oraz pochodnych
fenylopropanu. Składniki olejków charakteryzuje różnorodne działanie biologiczne. W pracy …

β-紫罗兰酮的生物活性与其衍生物的构效关系研究进展.

祝纤纤, 仝涛 - Journal of Food Safety & Quality, 2023 - search.ebscohost.com
β-紫罗兰酮是形成维甲酸, 视黄醇, β-胡萝卜素和维生素A 基本核结构的环萜化合物,
主要来源于天然食物中. β-紫罗兰酮具有抗癌, 抗炎, 抗氧化, 抗锥虫, 驱虫等多种生物活性, β …

Discovery of β-ionone derived chalcones as potent anti-aging agents

Y Wang, X Fan, J Zhang, Y Ye, S Xing, Q Zhu… - Phytochemistry …, 2023 - Elsevier
The accumulation of free radicals and consequent oxidative stress are primary drivers of
aging. As such, antioxidants that eliminate free radicals may achieve anti-aging effects. To …