The endothelium: gatekeeper to lung ischemia-reperfusion injury
HQ Ta, M Kuppusamy, SK Sonkusare, ME Roeser… - Respiratory …, 2024 - Springer
The success of lung transplantation is limited by the high rate of primary graft dysfunction
due to ischemia-reperfusion injury (IRI). Lung IRI is characterized by a robust inflammatory …
due to ischemia-reperfusion injury (IRI). Lung IRI is characterized by a robust inflammatory …
Transient receptor potential vanilloid 4 channel inhibition attenuates lung ischemia-reperfusion injury in a porcine lung transplant model
RJ Strobel, HQ Ta, AM Young, AM Wisniewski… - The Journal of Thoracic …, 2024 - Elsevier
Objective Transient receptor potential vanilloid 4 (TRPV4) is a nonselective cation channel
important in many physiological and pathophysiological processes, including pulmonary …
important in many physiological and pathophysiological processes, including pulmonary …
TRPV4-Expressing Tissue-Resident Macrophages Regulate the Function of Collecting Lymphatic Vessels via Thromboxane A2 Receptors in Lymphatic Muscle Cells
ME Schulz, VL Akerstrom, K Song, SE Broyhill, M Li… - bioRxiv, 2024 - biorxiv.org
Rationale: TRPV4 channels are critical regulators of blood vascular function and have been
shown to be dysregulated in many disease conditions in association with inflammation and …
shown to be dysregulated in many disease conditions in association with inflammation and …
Activation Of Endothelial Transient Receptor Potential Vanilloid 4 Exacerbates Myocardial Ischemia-Reperfusion Injury Via Vascular Integrity Impairment
M Zhang, Y Zou, H Ruan, Y Chen, Z Li, Y Liu… - Available at SSRN … - papers.ssrn.com
Background: Transient Receptor Potential Vanilloid 4 (TRPV4) activation exacerbates
myocardial ischemia-reperfusion (IR) injury and is abundantly expressed in vascular …
myocardial ischemia-reperfusion (IR) injury and is abundantly expressed in vascular …