Hypoxia is an important feature of the tumor microenvironment, and is closely associated
with cell proliferation, angiogenesis, metabolism and the tumor immune response. All these …

Molecular imaging has experienced enormous advancements in the areas of imaging
technology, imaging probe and contrast development, and data quality, as well as machine …

Photodynamic therapy (PDT) has been a preferred clinical technology for treating superficial
tumors due to its advantages of high selectivity, non-invasiveness and negligible drug …

Recent advances in targeted therapy and immunotherapy have once again raised the hope
that a cure might be within reach for many cancer types. Yet, most late-stage cancers are …

Background Cancer is characterized by the rampant proliferation, growth, and infiltration of
malignantly transformed cancer cells past their normal boundaries into adjacent tissues. It is …

Hypoxia development in tumor is closely associated with its increased aggressiveness and
strong resistance to therapy, leading to the poor prognosis in several cancer types …

Photodynamic therapy (PDT) is an emerging technology for tumor treatment in which
photosensitizer (PS)-mediated light irradiation reduces oxygen, producing high levels of …

Advantages such as strong signal strength, resistance to photobleaching, tunable
fluorescence emissions, high sensitivity, and biocompatibility are the driving forces for the …

Nanomedicines overcome the pharmacokinetic limitations of traditional drug formulations
and have promising prospect in cancer treatment. However, nanomedicine delivery in vivo is …

The extracellular milieu of tumors is generally assumed to be immunosuppressive due in
part to metabolic factors. Here, we review methods for probing the tumor metabolic …