What method to use for protein–protein docking?

KA Porter, I Desta, D Kozakov, S Vajda - Current opinion in structural …, 2019 - Elsevier
Highlights•The best servers based on “free” docking methods find acceptable models
among the top 10 predictions for around 40% of the targets.•Re-ranking the predictions by a …

Search strategies and evaluation in protein–protein docking: principles, advances and challenges

SY Huang - Drug discovery today, 2014 - Elsevier
Highlights•Search strategies of current protein–protein docking algorithms were
reviewed.•Challenges and future directions of established approaches were discussed.•Post …

The ClusPro web server for protein–protein docking

D Kozakov, DR Hall, B Xia, KA Porter, D Padhorny… - Nature protocols, 2017 - nature.com
Abstract The ClusPro server (https://cluspro. org) is a widely used tool for protein–protein
docking. The server provides a simple home page for basic use, requiring only two files in …

New additions to the C lus P ro server motivated by CAPRI

S Vajda, C Yueh, D Beglov, T Bohnuud… - Proteins: Structure …, 2017 - Wiley Online Library
The heavily used protein–protein docking server ClusPro performs three computational
steps as follows:(1) rigid body docking,(2) RMSD based clustering of the 1000 lowest energy …

Updates to the integrated protein–protein interaction benchmarks: docking benchmark version 5 and affinity benchmark version 2

T Vreven, IH Moal, A Vangone, BG Pierce… - Journal of molecular …, 2015 - Elsevier
We present an updated and integrated version of our widely used protein–protein docking
and binding affinity benchmarks. The benchmarks consist of non-redundant, high-quality …

How good is automated protein docking?

D Kozakov, D Beglov, T Bohnuud… - Proteins: Structure …, 2013 - Wiley Online Library
The protein docking server ClusPro has been participating in critical assessment of
prediction of interactions (CAPRI) since its introduction in 2004. This article evaluates the …

PatchDock and SymmDock: servers for rigid and symmetric docking

D Schneidman-Duhovny, Y Inbar… - Nucleic acids …, 2005 - academic.oup.com
Here, we describe two freely available web servers for molecular docking. The PatchDock
method performs structure prediction of protein–protein and protein–small molecule …

ZDOCK: an initial‐stage protein‐docking algorithm

R Chen, L Li, Z Weng - Proteins: Structure, Function, and …, 2003 - Wiley Online Library
The development of scoring functions is of great importance to protein docking. Here we
present a new scoring function for the initial stage of unbound docking. It combines our …

Protein–protein docking with simultaneous optimization of rigid-body displacement and side-chain conformations

JJ Gray, S Moughon, C Wang… - Journal of molecular …, 2003 - Elsevier
Protein–protein docking algorithms provide a means to elucidate structural details for
presently unknown complexes. Here, we present and evaluate a new method to predict …

PIPER: an FFT‐based protein docking program with pairwise potentials

D Kozakov, R Brenke, SR Comeau… - … Structure, Function, and …, 2006 - Wiley Online Library
Abstract The Fast Fourier Transform (FFT) correlation approach to protein–protein docking
can evaluate the energies of billions of docked conformations on a grid if the energy is …