[HTML][HTML] DNA damage and repair following traumatic brain injury

CK Davis, R Vemuganti - Neurobiology of Disease, 2021 - Elsevier
Traumatic brain injury (TBI) is known to promote significant DNA damage irrespective of age,
sex, and species. Chemical as well as structural DNA modification start within minutes and …

创伤性脑损伤相关神经炎症的研究进展.

宋鸽, 刘晓银, 史新宇, 叶益超… - Tianjin Medical …, 2020 - search.ebscohost.com
创伤性脑损伤(TBI) 发生时, 外力立即造成神经系统损害. 这种原发性损伤触发了体内生化级联
以及新陈代谢和细胞变化在内的继发性神经损害, 称为继发性脑损伤. TBI …

DNA methylation-mediated Mfn2 gene regulation in the brain: a role in brain trauma-induced mitochondrial dysfunction and memory deficits

PG Kulkarni, N Balasubramanian, R Manjrekar… - Cellular and Molecular …, 2023 - Springer
Repeated mild traumatic brain injuries (rMTBI) affect mitochondrial homeostasis in the brain.
However, mechanisms of long-lasting neurobehavioral effects of rMTBI are largely unknown …

Repeated mild traumatic brain injuries perturb the mitochondrial biogenesis via DNA methylation in the hippocampus of rat

N Balasubramanian, G Jadhav, AJ Sakharkar - Mitochondrion, 2021 - Elsevier
Mitochondrial biogenesis in the brain is impaired in various neurological disorders including
traumatic brain injury (TBI). The long-lasting effects of TBI may be, in part, attributed to …

[HTML][HTML] Epigenetic blockade of hippocampal SOD2 via DNMT3b-mediated DNA methylation: implications in mild traumatic brain injury-induced persistent oxidative …

N Balasubramanian, S Sagarkar, AG Choudhary… - Molecular …, 2021 - Springer
The recurrent events of mild trauma exacerbate the vulnerability for post-traumatic stress
disorder; however, the underlying molecular mechanisms are scarcely known. The repeated …

Antioxidant Biomarkers and Nutraceutical Therapeutics in Neurodegeneration and Neurotrauma

LA Koza - 2022 - search.proquest.com
Mild traumatic brain injury (mTBI), yielding a Glascow Coma Scale of 13-15, is the most
commonly occurring severity of TBI. Pathology from mTBI consists of blood brain barrier …

[PDF][PDF] Mitochondria, Inflammation, and T-Cell Metabolism in a Rat Model of Pediatric Mild Traumatic Brain Injury

EA Fraunberger - 2020 - prism.ucalgary.ca
Representing approximately 20,000 emergency department visits in Canada every year,
pediatric traumatic brain injury (TBI) can be an intractable medical problem with limited …