Many processes in the human body—including brain function—are regulated over the 24-
hour cycle, and there are strong associations between disrupted circadian rhythms (for …

Complex multicellular organisms, such as mammals, express two complete sets of
chromosomes per nucleus, combining the genetic material of both parents. However …

Autism spectrum disorder (ASD) has a major impact on the development and social
integration of affected individuals and is the most heritable of psychiatric disorders. An …

Abstract Background Prader–Willi syndrome (PWS) is a complex neuroendocrine disorder
affecting approximately 1/15,000–1/30,000 people. Unmet medical needs of individuals with …

The nucleolus of mammalian cells contains hundreds of box C/D small nucleolar RNAs
(SNORDs). Through their ability to base pair with ribosomal RNA precursors, most play …

Small nucleolar RNAs (snoRNAs) play critical roles in various biological processes. The
aberrant expression or depletion of snoRNAs is related to various diseases. In previous …

Prader-Willi syndrome (PWS) is an imprinted neurodevelopmental disease caused by a loss
of paternal genes on chromosome 15q11-q13. It is characterized by cognitive impairments …

Non-mendelian inheritance refers to the group of phenomena and observations related to
the inheritance of genetic information that cannot be merely explained by Mendel's laws of …

Abstract Purpose of Review This paper reviews how sleep is impacted in patients with
Prader-Willi syndrome (PWS), focusing on sleep-related breathing disturbances and …

Addictive disorders have been much investigated and many studies have underlined the
role of environmental factors such as social interaction in the vulnerability to and …